Update on Nanoparticle-Based Drug Delivery System for Anti-inflammatory Treatment

被引：73
作者：
Wang, Huailan [1 ]
Zhou, Yunxiang [2 ]
Sun, Qunan [3 ]
Zhou, Chenghao [1 ]
Hu, Shiyao [4 ]
Lenahan, Cameron [5 ,6 ]
Xu, Weilin [7 ]
Deng, Yongchuan [2 ]
Li, Gonghui [1 ]
Tao, Sifeng [2 ]
机构：
[1] Zhejiang Univ, Sch Med, Sir Run Run Shaw Hosp, Dept Urol, Hangzhou, Peoples R China
[2] Zhejiang Univ, Sch Med, Affiliated Hosp 2, Dept Surg Oncol, Hangzhou, Peoples R China
[3] Zhejiang Univ, Sch Med, Affiliated Hosp 2, Dept Med Oncol, Hangzhou, Peoples R China
[4] Zhejiang Univ, Sch Med, Hangzhou, Peoples R China
[5] Loma Linda Univ, Sch Med, Ctr Neurosci Res, Loma Linda, CA USA
[6] Burrell Coll Osteopath Med, Las Cruces, NM USA
[7] Zhejiang Univ, Sch Med, Affiliated Hosp 2, Dept Neurosurg, Hangzhou, Peoples R China
来源：
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY | 2021年 / 9卷
关键词：
nanoparticle; anti-inflammatory; drug delivery; organic NPs; inorganic NPs; inflammatory disease; IN-VITRO CYTOTOXICITY; INFLAMMATION; MACROPHAGES; FORMULATION; HEMORRHAGE; CYTOKINES; PEPTIDES; EXOSOMES; THERAPY; IMPLANT;
D O I：
10.3389/fbioe.2021.630352
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Nanobiotechnology plays an important role in drug delivery, and various kinds of nanoparticles have demonstrated new properties, which may provide opportunities in clinical treatment. Nanoparticle-mediated drug delivery systems have been used in anti-inflammatory therapies. Diseases, such as inflammatory bowel disease, rheumatoid arthritis, and osteoarthritis have been widely impacted by the pathogenesis of inflammation. Efficient delivery of anti-inflammatory drugs can reduce medical dosage and improve therapeutic effect. In this review, we discuss nanoparticles with potential anti-inflammatory activity, and we present a future perspective regarding the application of nanomedicine in inflammatory diseases.
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页数：9
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