Tumefactive intracranial presentation of precursor B-cell acute lymphoblastic leukemia

被引：4

作者：

Forester, Craig M.

Braunreiter, Chi L. ^{[2
]}

Yaish, Hasan ^{[2
]}

Hedlund, Gary L. ^{[1
]}

Afify, Zeinab ^{[2
]}

机构：

[1] Primary Childrens Med Ctr, Dept Pediat Radiol, Salt Lake City, UT 84113 USA

[2] Univ Utah, Primary Childrens Med Ctr, Div Pediat Hematol Oncol, Salt Lake City, UT USA

来源：

PEDIATRIC RADIOLOGY | 2009年 / 39卷 / 11期

关键词：

ALL; CNS; Leukemia; MRS; MRI; Child; MR; FEATURES;

D O I：

10.1007/s00247-009-1347-x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

In children, leukemia is the most common malignancy, and approximately 75% of leukemias are acute lymphoblastic leukemia (ALL). Central nervous system leukemia is found at diagnosis in fewer than 5% of children with ALL. Leukemic intracranial masses have been described with acute myeloid leukemia, but ALL presenting as a mass lesion is rare. We describe a unique case of an intracranial confirmed precursor B cell (pre-B) ALL mass in a 13-year-old girl that was diagnosed by brain CT, MRI and cerebral angiography, and confirmed by biopsy. This report details pertinent history and distinguishing imaging features of an intracranial ALL tumefaction.

引用

页码：1230 / 1233

页数：4

共 8 条

[1]

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[2]

BLEYER WA, 1989, AM J PEDIAT HEMATOL, V11, P57

[3]

Chiechi MV, 1996, AM J NEURORADIOL, V17, P1365

[4] Multiple intracranial tumors in Philadelphia chromosome positive acute lymphoblastic leukemia: Successful treatment following aggressive supportive care, early cranial radiation, high dose chemotherapy and imatinib [J].