Hepatic glutathione S-transferase activity in flounder collected from contaminated and reference sites along the Polish coast

被引:17
作者
Napierska, Dorota
Kopecka, Justyna
Podolska, Magdalena
Pempkowiak, Janusz
机构
[1] Sea Fisheries Res Inst, Dept Fishery Oceanog & Marine Ecol, PL-81332 Gdynia, Poland
[2] PAS, Inst Oceanol, PL-81712 Sopot, Poland
关键词
glutathione S-transferase; biomarker; contamination; field-collected fish; flounder; Platichthys flesus; southern Baltic Sea;
D O I
10.1016/j.ecoenv.2005.07.022
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The aim of the present study was to examine the activity of hepatic glutathione S-transferase (GST) in flounder, Platichthys flesus, as a potential biomarker of exposure to xenobiotics present in the environment. The fish were collected along known pollution gradients and from areas regarded relatively free of anthropogenic input. GST was measured spectrophotometrically in each sampled specimen of flounder. The databases from the studies performed by two research institutes were compiled, and generalized linear models were used to analyze the dependence of the enzyme activity on the time and area of sampling and on selected biological parameters of the fish. Fish sex, sampling area, year, month, water temperature, and somatic indices (gonado-somatic index, hepato-somatic index) were significant in the model of GST activity. The three annual datasets showed that the biomarker activities exhibited in the Gulf of Gdansk were significantly different from those measured in the areas off the coast. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:355 / 363
页数:9
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