Damage control resuscitation in pediatric trauma

被引:14
作者
Gilley, Meghan [1 ]
Beno, Suzanne [1 ]
机构
[1] Univ Toronto, Hosp Sick Children, Div Emergency Med, 525 Univ Ave, Toronto, ON M5G 1X8, Canada
关键词
damage control resuscitation; massive transfusion protocol; pediatric trauma; MASSIVE TRANSFUSION PROTOCOL; TRANEXAMIC ACID; HEMOSTATIC RESUSCITATION; EARLY COAGULOPATHY; BLOOD; TIME; MORTALITY; CHILDREN; RATIO;
D O I
10.1097/MOP.0000000000000617
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Purpose of reviewDamage control resuscitation is an overall management strategy used in trauma patients to rapidly restore physiologic stability, while mitigating hypothermia, coagulopathy and acidosis. We review the evidence and current practice of damage control resuscitation in pediatric trauma patients with a specific focus on fluid management.Recent findingsThere have been a number of studies over the last several years examining crystalloid fluid resuscitation, balanced blood product transfusion practice and hemostatic agents in pediatric trauma. Excessive fluid resuscitation has been linked to increased number of ICU days, ventilator days and mortality. Balanced massive transfusion (1:1:1 product ratio) has not yet been demonstrated to have the same mortality benefits in pediatric trauma patients as in adults. Similarly, tranexamic acid (TXA) has strong evidence to support its use in adult trauma and some evidence in pediatric trauma.SummaryAttention to establishing rapid vascular access and correcting hypothermia and acidosis is essential. A judicious approach to crystalloid resuscitation in the bleeding pediatric trauma patient with early use of blood products in keeping with an organized approach to massive hemorrhage is recommended. The ideal crystalloid volumes and/or blood product ratios in pediatric trauma patients have yet to be determined.
引用
收藏
页码:338 / 343
页数:6
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