Anomalous diffusion in living yeast cells

被引:340
作者
Tolic-Norrelykke, IM
Munteanu, EL
Thon, G
Oddershede, L
Berg-Sorensen, K
机构
[1] Niels Bohr Inst, DK-2100 Copenhagen O, Denmark
[2] Inst Mol Biol, DK-1353 Copenhagen K, Denmark
[3] Rudjer Boskovic Inst, HR-10000 Zagreb, Croatia
关键词
D O I
10.1103/PhysRevLett.93.078102
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
The viscoelastic properties of the cytoplasm of living yeast cells were investigated by studying the motion of lipid granules naturally occurring in the cytoplasm. A large frequency range of observation was obtained by a combination of video-based and laser-based tracking methods. At time scales from 10(-4) to 10(2) s, the granules typically perform subdiffusive motion with characteristics different from previous measurements in living cells. This subdiffusive behavior is thought to be due to the presence of polymer networks and membranous structures in the cytoplasm. Consistent with this hypothesis, we observe that the motion becomes less subdiffusive upon actin disruption.
引用
收藏
页码:078102 / 1
页数:4
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