Metal-free C-H arylation of imidazoheterocycles with aryl hydrazines

被引：21

作者：

Jana, Sourav ^{[1
]}

Samanta, Sadhanendu ^{[1
]}

Bagdi, Avik K. ^{[2
]}

Shirinian, Valerii Z. ^{[3
]}

Hajra, Alakananda ^{[1
]}

机构：

[1] Visva Bharati A Cent Univ, Dept Chem, Santini Ketan 731235, W Bengal, India

[2] TDB Coll, Dept Chem, Burdwan 713347, W Bengal, India

[3] Zelinsky Inst Organ Chem RAS, 47 Leninsky Prosp, Moscow 119991, Russia

来源：

RSC ADVANCES | 2018年 / 8卷 / 22期

基金：

俄罗斯基础研究基金会;

关键词：

CATALYZED DIRECT ARYLATION; FREE COUPLING REACTIONS; RADICAL ARYLATION; BOND FORMATION; C-3; ARYLATION; ONE-POT; PALLADIUM; COPPER; ARYLHYDRAZINES; FUNCTIONALIZATION;

D O I：

10.1039/c8ra01474d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and efficient metal-free arylation of imidazo[1,2-a] pyridines at the C-3 position with arylhydrazine has been achieved at room temperature under ambient air conditions. Various 2,3-disubstituted imidazopyridines and imidazothiazoles were synthesized with high yields. The present methodology demonstrates the usefulness of commercially available aryl hydrazine as an arylating agent.

引用

页码：12360 / 12367

页数：8

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