Spent culture supernatant of Mycobacterium tuberculosis H37Ra improves viability of aged cultures of this strain and allows small inocula to initiate growth

被引：39

作者：

Sun, ZH ^{[1
]}

Zhang, Y ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD 21205 USA

来源：

JOURNAL OF BACTERIOLOGY | 1999年 / 181卷 / 24期

关键词：

D O I：

10.1128/JB.181.24.7626-7628.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Spent culture supernatant from early-stationary-phase Mycobacterium tuberculosis H37Ra cultures increased the viability of bacilli from aged cultures of this strain and allowed small inocula to initiate growth in liquid culture. The resuscitation factor was acid labile and heat stable, with a mass of less than 1,375 Da.

引用

页码：7626 / 7628

页数：3

共 9 条

[1] PHYLOGENETIC IDENTIFICATION AND IN-SITU DETECTION OF INDIVIDUAL MICROBIAL-CELLS WITHOUT CULTIVATION [J].

AMANN, RI ;

LUDWIG, W ;

SCHLEIFER, KH .

MICROBIOLOGICAL REVIEWS, 1995, 59 (01) :143-169

[2]

[Anonymous], 1967, Adv Microb Physiol, DOI DOI 10.1016/S0065-2911(08)60248-9

[3] FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA [J].

DUBOS, RJ ;

DAVIS, BD .

JOURNAL OF EXPERIMENTAL MEDICINE, 1946, 83 (05) :409-423

[4] DORMANCY IN STATIONARY-PHASE CULTURES OF MICROCOCCUS-LUTEUS - FLOW CYTOMETRIC ANALYSIS OF STARVATION AND RESUSCITATION [J].

KAPRELYANTS, AS ;

KELL, DB .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1993, 59 (10) :3187-3196

[5]

KVACH JT, 1982, INT J LEPROSY, V50, P183

[6] MICROBIAL PERSISTENCE .I. CAPACITY OF TUBERCLE BACILLI TO SURVIVE STERILIZATION IN MOUSE TISSUES [J].

MCCUNE, RM ;

FELDMANN, FM ;

LAMBERT, HP ;

MCDERMOTT, W .

JOURNAL OF EXPERIMENTAL MEDICINE, 1966, 123 (03) :445-+

[7] A bacterial cytokine [J].

Mukamolova, GV ;

Kaprelyants, AS ;

Young, DI ;

Young, M ;

Kell, DB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (15) :8916-8921

[8] INFLUENCE OF VIABLE CELLS ON THE RESUSCITATION OF DORMANT CELLS IN MICROCOCCUS-LUTEUS CULTURES HELD IN AN EXTENDED STATIONARY-PHASE - THE POPULATION EFFECT [J].

VOTYAKOVA, TV ;

KAPRELYANTS, AS ;

KELL, DB .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1994, 60 (09) :3284-3291

[9] Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide [J].

Zhang, Y ;

Scorpio, A ;

Nikaido, H ;

Sun, ZH .

JOURNAL OF BACTERIOLOGY, 1999, 181 (07) :2044-2049

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