Background: The aim of this study is to identify the risk factors that are associated with suicide attempts in patients with bipolar disorder type I. Subjects and methods: This cross-sectional study was conducted with inpatients and outpatients with BD type I. Patients who met the study inclusion criteria (n=91) were evaluated in terms of sociodemographic variables, history of childhood trauma, comorbidity of adult attention deficit hyperactivity disorder and posttraumatic stress disorder, and the course of the disease. The patients were divided into two groups: those with a history of suicide attempts and those without a history of suicide attempts. The parameters of the study groups were compared with t and chi-square tests as appropriate. Logistic regression was used to identify the predictors of suicide attempt. Results: Logistic regression analysis of the study parameters suggested that the number of major depressive episodes (odds ratio: 7.18; 95% confidence interval: 1.84-28) and history of emotional neglect (odds ratio: 1.83; 95% confidence interval: 1.15-2.90) were significant predictors of suicide attempt in patients with BD. Conclusion: In BD type I patients with a history of suicide attempts, the number of depressive episodes and emotional neglect, a subtype of childhood traumas, were the most remarkable risk factors. Considering the frequency of depressive episodes during the course of the disease and assessing traumas including those in childhood may help predict future suicide attempts in patients with BD.
机构:
Univ Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, BrazilUniv Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, Brazil
de Abreu, Lena Nabuco
Nery, Fabiano G.
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Univ Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, BrazilUniv Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, Brazil
Nery, Fabiano G.
Harkavy-Friedman, Jill M.
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Columbia Univ, Dept Psychiat, Mol Imaging & Neuropathol Div, New York, NY USA
New York State Psychiat Inst & Hosp, New York, NY 10032 USAUniv Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, Brazil
Harkavy-Friedman, Jill M.
de Almeida, Karla Matias
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Univ Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, BrazilUniv Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, Brazil
de Almeida, Karla Matias
Gomes, Bernardo Carramao
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Univ Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, BrazilUniv Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, Brazil
Gomes, Bernardo Carramao
Oquendo, Maria A.
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Columbia Univ, Dept Psychiat, Mol Imaging & Neuropathol Div, New York, NY USA
New York State Psychiat Inst & Hosp, New York, NY 10032 USAUniv Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, Brazil
Oquendo, Maria A.
Lafer, Beny
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Univ Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, BrazilUniv Sao Paulo, Bipolar Disorder Res Program, Dept Psychiat, Sch Med, Sao Paulo, Brazil
机构:
Univ Sao Paulo, Sch Med, Inst Psychiat, Psychol Unit, Sao Paulo, Brazil
Univ Sao Paulo, Sch Med, Inst Psychiat, Neuropsychol Unit, Sao Paulo, Brazil
Univ Sao Paulo, Sch Med, Inst Psychiat, Bipolar Disorder Res Program, Sao Paulo, BrazilUniv Sao Paulo, Sch Med, Inst Psychiat, Psychol Unit, Sao Paulo, Brazil
de Almeida Rocca, Cristiana Castartho
Gerchmann, Luciana
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Univ Sao Paulo, Sch Med, Inst Psychiat, Psychol Unit, Sao Paulo, Brazil
Univ Sao Paulo, Sch Med, Inst Psychiat, Neuropsychol Unit, Sao Paulo, Brazil
Univ Sao Paulo, Sch Med, Inst Psychiat, Bipolar Disorder Res Program, Sao Paulo, BrazilUniv Sao Paulo, Sch Med, Inst Psychiat, Psychol Unit, Sao Paulo, Brazil
Gerchmann, Luciana
de Abreu, Lena Nabuco
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Univ Sao Paulo, Sch Med, Inst Psychiat, Bipolar Disorder Res Program, Sao Paulo, BrazilUniv Sao Paulo, Sch Med, Inst Psychiat, Psychol Unit, Sao Paulo, Brazil
de Abreu, Lena Nabuco
Lafer, Beny
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Univ Sao Paulo, Sch Med, Inst Psychiat, Bipolar Disorder Res Program, Sao Paulo, Brazil
Univ Sao Paulo, Sch Med, Dept Psychiat, Sao Paulo, BrazilUniv Sao Paulo, Sch Med, Inst Psychiat, Psychol Unit, Sao Paulo, Brazil
机构:
Sri Balaji Vidyapeeth Deemed To Be Univ, Mahatma Gandhi Med Coll & Res Inst, Dept Psychiat, Pillayarkuppam 607403, Puducherry, IndiaSri Balaji Vidyapeeth Deemed To Be Univ, Mahatma Gandhi Med Coll & Res Inst, Dept Psychiat, Pillayarkuppam 607403, Puducherry, India
Subramanian, Karthick
Menon, Vikas
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JIPMER, Dept Psychiat, Pondicherry, IndiaSri Balaji Vidyapeeth Deemed To Be Univ, Mahatma Gandhi Med Coll & Res Inst, Dept Psychiat, Pillayarkuppam 607403, Puducherry, India
Menon, Vikas
Sarkar, Siddharth
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机构:
All India Inst Med Sci, Dept Psychiat, New Delhi, India
All India Inst Med Sci, NDDTC, New Delhi, IndiaSri Balaji Vidyapeeth Deemed To Be Univ, Mahatma Gandhi Med Coll & Res Inst, Dept Psychiat, Pillayarkuppam 607403, Puducherry, India
Sarkar, Siddharth
Chandrasekaran, Vigneshvar
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Sri Balaji Vidyapeeth Deemed To Be Univ, Mahatma Gandhi Med Coll & Res Inst, Dept Psychiat, Pillayarkuppam 607403, Puducherry, IndiaSri Balaji Vidyapeeth Deemed To Be Univ, Mahatma Gandhi Med Coll & Res Inst, Dept Psychiat, Pillayarkuppam 607403, Puducherry, India
Chandrasekaran, Vigneshvar
Selvakumar, Nivedhitha
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机构:
JIPMER, Dept Psychiat, Pondicherry, IndiaSri Balaji Vidyapeeth Deemed To Be Univ, Mahatma Gandhi Med Coll & Res Inst, Dept Psychiat, Pillayarkuppam 607403, Puducherry, India
机构:
Univ Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy
Harvard Med Sch, Dept Psychiat, Belmont, MA 02478 USA
Massachusetts Gen Hosp, Int Consortium Bipolar Disorder Res, McLean Div, Belmont, MA 02478 USAUniv Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy
Pompili, Maurizio
Tondo, Leonardo
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机构:
Harvard Med Sch, Dept Psychiat, Belmont, MA 02478 USA
Massachusetts Gen Hosp, Int Consortium Bipolar Disorder Res, McLean Div, Belmont, MA 02478 USA
Univ Cagliari, Ctr Lucio Bini Mood Disorders Res Ctr, Dept Psychol, Cagliari, Sardinia, ItalyUniv Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy
Tondo, Leonardo
Grispini, Alessandro
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机构:
Univ Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, ItalyUniv Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy
Grispini, Alessandro
De Pisa, Eleonora
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机构:Univ Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy
De Pisa, Eleonora
Lester, David
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机构:
Ctr Study Suicide, Blackwood, NJ USAUniv Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy
Lester, David
Angeletti, Gloria
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Univ Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, ItalyUniv Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy
Angeletti, Gloria
Buonocore, Letizia
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机构:
Univ Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, ItalyUniv Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy
Buonocore, Letizia
Girardi, Paolo
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Univ Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, ItalyUniv Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy
Girardi, Paolo
Tatarelli, Roberto
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Univ Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, ItalyUniv Roma La Sapienza, St Andrea Hosp, Dept Psychiat, Rome, Italy