Nano-copper catalyzed three-component reaction to construct 1,4-substituted 1,2,3-triazoles

被引：56

作者：

Huang, Lina ^{[1
]}

Liu, Wei ^{[1
]}

Wu, Juncheng ^{[1
]}

Fu, Ying ^{[1
]}

Wang, Kehu ^{[1
]}

Huo, Congde ^{[1
]}

Du, Zhengyin ^{[1
]}

机构：

[1] Northwest Normal Univ, Coll Chem & Chem Engn, Key Lab Polymer Mat Gansu Prov,Minist Educ, Key Lab Ecoenvironm Related Polymer Mat, Lanzhou 730070, Peoples R China

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 14期

关键词：

Copper nanoparticles; Phenylacetylene; Cycloaddition; Click chemistry; Multicomponent reaction; ONE-POT SYNTHESIS; BORONIC ACIDS; ARYL AZIDES; TERMINAL ALKYNES; AROMATIC RING; SODIUM-AZIDE; WATER; NANOPARTICLES; DERIVATIVES; PARTICLES;

D O I：

10.1016/j.tetlet.2014.02.114

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three-component reaction of alkyl halides, sodium azide with terminal alkynes can be catalyzed by nano-copper particles under ambient conditions. A series of 1,4-disubstituted-1,2,3-triazoles were obtained regioselectively by this one-pot strategy. Nano copper can be reused at least three times without significant deactivation. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：2312 / 2316

页数：5

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