Cyclopalladation of Schiff Bases from Methyl Esters of α-Amino Acids. Unexpected Activation of the O-Me Bond with Formation of a Bianionic Tridentate Metallacycle

被引：24
作者：
Albert, Joan [1 ,2 ]
Crespo, Margarita [1 ,2 ]
Granell, Jaume [1 ,2 ]
Rodriguez, Judit [1 ,2 ]
Zafrilla, Javier [1 ,2 ]
Calvet, Teresa [3 ]
Font-Bardia, Merce [3 ]
Solans, Xavier [3 ]
机构：
[1] Univ Barcelona, Dept Quim Inorgan, Barcelona 08028, Spain
[2] Univ Barcelona, Inst Biomed IBUB, E-08028 Barcelona, Spain
[3] Univ Barcelona, Dept Cristallog Mineral & Diposits Minerals, E-08028 Barcelona, Spain
来源：
ORGANOMETALLICS | 2010年 / 29卷 / 01期
关键词：
PD-C BOND; BIOLOGICALLY IMPORTANT LIGANDS; RAY CRYSTAL-STRUCTURE; CARBON-MONOXIDE; METAL-COMPLEXES; BIOORGANOMETALLIC CHEMISTRY; CYCLOMETALATED COMPLEXES; PALLADIUM(II) COMPLEXES; N-BENZYLIDENEAMINES; OXIDATIVE ADDITION;
D O I：
10.1021/om9009153
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The action of palladium acetate on imines from methyl esters of the alpha-amino acids glycine, alanine, valine, and tyrosine is herein described. The reactivity of the new metallacycles obtained with phosphines and amines is also described, as well as the synthesis of isoquinolinium salts by insertion of diphenylacetylene into the Pd-C bond. Besides this, the unexpected activation of the Me-O bond of the ester group of the amino acid fragment is also reported, in a process that affords new cyclopalladated derivatives having the metalated molecule as a dianionic (C,N,O) ligand.
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收藏
页码：214 / 225
页数：12
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