The lipid transfer proteins (LTP) essentially concentrate in the skin of Rosaceae fruits as cell surface exposed allergens

被引：54
作者：
Borges, J. -P.
Jauneau, A.
Brule, C.
Culerrier, R.
Barre, A.
Didier, A.
Rouge, P.
机构：
[1] CNRS, UPS, UMR 5546, F-31326 Castanet Tolosan, France
[2] CHU Larrey, Clin Voies Resp, F-31059 Toulouse 09, France
来源：
PLANT PHYSIOLOGY AND BIOCHEMISTRY | 2006年 / 44卷 / 10期
关键词：
Mal d 3; Pru p 3; Pru d 3; Pru ar 3; alergen; lipid transfer protein; Rosaceae fruit;
D O I：
10.1016/j.plaphy.2006.09.018
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The localization and distribution of non-specific lipid transfer proteins (nsLTP) allergens in the skin and pulp of Rosaceae fruits (apple, peach, apricot, plum) has been investigated. nsLTP essentially concentrate in the pericarp of the fruits whereas the pulp contains lower amounts of allergens. Immuno localization showed they are primarily located in the cytosol but are subsequently excreted and finally accumulate at the plasmalemma-cell wall interface and in the cell wall. However, high discrepancies were observed in the content of allergens among, e.g. different cultivars of apple. As a consequence, the consumption of peeled-off fruits is recommended to reduce the risk of severe allergic reactions (anaphylactic shock) in individuals sensitized to Rosaceae fruits. (c) 2006 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：535 / 542
页数：8
相关论文
共 45 条
  • [1] Analysis of the heat stability of lipid transfer protein from apple
    Asero, R
    Mistrello, G
    Roncarolo, D
    Amato, S
    Falagiani, P
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2003, 112 (05) : 1009 - 1011
  • [2] Lipid transfer protein: A pan-allergen in plant-derived foods that is highly resistant to pepsin digestion
    Asero, R
    Mistrello, G
    Roncarolo, D
    de Vries, SC
    Gautier, MF
    Ciurana, CLF
    Verbeek, E
    Mohammadi, T
    Knul-Brettlova, V
    Akkerdaas, JH
    Bulder, I
    Aalberse, RC
    van Ree, R
    [J]. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 2001, 124 (1-3) : 67 - 69
  • [3] ASERO R, 2006, ALLERG IMMUNOL PARIS, V38, P118
  • [4] Lipid transfer protein as a potential panallergen?
    Ballmer-Weber, BK
    [J]. ALLERGY, 2002, 57 (10) : 873 - 875
  • [5] Proteomics of loosely bound cell wall proteins of Arabidopsis thaliana cell suspension cultures:: A critical analysis
    Borderies, G
    Jamet, E
    Lafitte, C
    Rossignol, M
    Jauneau, A
    Boudart, G
    Monsarrat, B
    Esquerrè-Tugayé, MT
    Boudet, A
    Pont-Lezica, R
    [J]. ELECTROPHORESIS, 2003, 24 (19-20) : 3421 - 3432
  • [6] Presence of allergenic proteins in different peach (Prunus persica) cultivars and dependence of their content on fruit ripening
    Brenna, OV
    Pastorello, EA
    Farioli, L
    Pravettoni, V
    Pompei, C
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (26) : 7997 - 8000
  • [7] Pru p 3 (LTP) content in peach extracts
    Carnés, J
    Fernández-Caldas, E
    Gallego, MT
    Ferrer, A
    Cuesta-Herranz, J
    [J]. ALLERGY, 2002, 57 (11) : 1071 - 1075
  • [8] Solution structure of a tobacco lipid transfer protein exhibiting new biophysical and biological features
    Da Silva, P
    Landon, C
    Industri, B
    Marais, A
    Marion, D
    Ponchet, M
    Vovelle, F
    [J]. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2005, 59 (02) : 356 - 367
  • [9] Clinically relevant peach allergy is related to peach lipid transfer protein, Pru p 3, in the Spanish population
    Fernández-Rivas, M
    González-Mancebo, E
    Rodriguez-Pérez, R
    Benito, C
    Sánchez-Monge, R
    Salcedo, G
    Alonso, D
    Rosado, A
    Tejedor, MA
    Vila, C
    Casas, ML
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2003, 112 (04) : 789 - 795
  • [10] CALCULATION OF ELECTROSTATIC POTENTIALS IN AN ENZYME ACTIVE-SITE
    GILSON, MK
    HONIG, BH
    [J]. NATURE, 1987, 330 (6143) : 84 - 86
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