Effect of supplemental oral L-arginine on exercise capacity in patients with stable angina pectoris

被引：121

作者：

Ceremuzynski, L

Chamiec, T

HerbaczynskaCedro, K

机构：

[1] POLISH ACAD SCI,MED RES CTR,WARSAW,POLAND

[2] POSTGRAD MED SCH,DEPT CARDIOL,WARSAW,POLAND

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1997年 / 80卷 / 03期

关键词：

D O I：

10.1016/S0002-9149(97)00354-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A randomized, double-blind, placebo-controlled study in patients with clinical symptoms of stable angina pectoris and healed myocardial infarction (n = 22) has shown that oral supplementation with L-arginine (6 g/day for 3 days) increases exercise capacity (tested on a Marquette case 12 treadmill according to the modified Bruce protocol). Results suggest that the inefficient L-arginine/nitric oxide system contributes to limitation of myocardial perfusion and/or peripheral vasodilation during maximum exercise in patients with stable angina pectoris.

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页码：331 / &

页数：7

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