Characterization of the CtsR Stress Response Regulon in Lactobacillus plantarum

被引：62
作者：
Fiocco, Daniela [2 ]
Capozzi, Vittorio [1 ]
Collins, Michael [5 ]
Gallone, Anna [2 ]
Hols, Pascal [3 ]
Guzzo, Jean [4 ]
Weidmann, Stephanie [4 ]
Rieu, Aurelie [4 ]
Msadek, Tarek [5 ]
Spano, Giuseppe [1 ]
机构：
[1] Univ Foggia, Dept Food Sci, I-71100 Foggia, Italy
[2] Univ Foggia, Dept Biomed Sci, I-71100 Foggia, Italy
[3] Catholic Univ Louvain, ISV, Unite Genet, B-1348 Louvain, Belgium
[4] Univ Bourgogne, Inst Jules Guyot, REVV, Dijon, France
[5] CNRS, Dept Microbiol, Inst Pasteur, URA 2172, F-75724 Paris 15, France
来源：
JOURNAL OF BACTERIOLOGY | 2010年 / 192卷 / 03期
关键词：
TRANSCRIPTION QUANTITATIVE PCR; COMPLETE GENOME SEQUENCE; NEGATIVE REGULATOR; INTERNAL CONTROL; GENE-EXPRESSION; SHOCK; HEAT; GROWTH; IDENTIFICATION; TOLERANCE;
D O I：
10.1128/JB.01122-09
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Lactobacillus plantarum ctsR was characterized. ctsR was found to be cotranscribed with clpC and induced in response to various abiotic stresses. ctsR deletion conferred a heat-sensitive phenotype with peculiar cell morphological features. The transcriptional pattern of putative CtsR regulon genes was examined in the Delta ctsR mutant. Direct CtsR-dependent regulation was demonstrated by DNA-binding assays using recombinant CtsR and the promoters of the ctsR-clpC operon and hsp1.
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收藏
页码：896 / 900
页数：5
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