The transmissible spongiform encephalopathies: emerging and declining epidemics

被引:27
作者
Manson, J. C.
Cancellotti, E.
Hart, P.
Bishop, M. T.
Barron, R. M.
机构
[1] Inst Anim Hlth, Neuropathogenesis Unit, Edinburgh EH9 3JF, Midlothian, Scotland
[2] Western Gen Hosp, Natl CJD Surveillance Unit, Edinburgh EH4 2XU, Midlothian, Scotland
基金
英国医学研究理事会;
关键词
bovine spongiform encephalopathy (BSE); chronic wasting disease (CWD); Creutzfeldt-Jakob disease (CJD); prion protein (PrP); scrapie; transmissible spongiform encephalopathy (TSE); CREUTZFELDT-JAKOB-DISEASE; CHRONIC WASTING DISEASE; BLOOD-TRANSFUSION; PRION DISEASES; BSE AGENT; MULE DEER; VARIANT CJD; SCRAPIE; SHEEP; MICE;
D O I
10.1042/BST0341155
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
TSEs (transmissible spongiform encephalopathies) are neurodegenerative diseases of various mammalian species, the best known of which include BSE (bovine spongiform encephalopathies) in cattle, CJD (Creutzfeldt-jakob disease) in humans, scrapie in sheep and CWD (chronic wasting disease) in deer. This review examines the emergence of various TSE strains and their transmission, and discusses disease surveillance and control.
引用
收藏
页码:1155 / 1158
页数:4
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