Workshop report: Schistosomiasis vaccine clinical development and product characteristics

被引：23

作者：

Mo, Annie X. ^{[1
]}

Colley, Daniel G. ^{[2
,3
]}

机构：

[1] NIAID, Div Microbiol & Infect Dis, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA

[2] Univ Georgia, Ctr Trop & Emerging Global Dis, Athens, GA 30602 USA

[3] Univ Georgia, Dept Microbiol, Athens, GA 30602 USA

来源：

VACCINE | 2016年 / 34卷 / 08期

关键词：

Schistosomiasis; Vaccine; Clinical development plan (CDP); Preferred product characteristics (PPC); Target product profile (TPP); THERAPEUTIC VACCINE; HOOKWORM VACCINE; ECONOMIC VALUE; HUMAN IGE; ELIMINATION; HAEMATOBIUM; CANDIDATE; INFECTION; RESPONSES; EFFICACY;

D O I：

10.1016/j.vaccine.2015.12.032

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A schistosomiasis vaccine meeting was organized to evaluate the utility of a vaccine in public health programs, to discuss clinical development paths, and to define basic product characteristics for desirable vaccines to be used in the context of schistosomiasis control and elimination programs. It was concluded that clinical evaluation of a schistosomiasis vaccine is feasible with appropriate trial design and tools. Some basic Preferred Product Characteristics (PPC) for a human schistosomiasis vaccine and for a veterinary vaccine for bovine use were also proposed.

引用

页码：995 / 1001

页数：7

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