Primary Sjogren's syndrome associated with pneumatosis cystoides coli

We report the case of a 43-year-old woman with primary Sjogren's syndrome, according to Americano-European criteria. Eighteen months after the diagnosis, the patient presented pneumatosis cystoides coli (PCC), which resolved with medical treatment consisting of diet and cisapride. Four years after this episode, the patient has not developed clinical features of another systemic inflammatory rheumatic disease and PCC has not relapsed. To the best of our knowledge, the association between primary Sjogren' syndrome and PCC has never been reported. Physiopathology and treatment of PCC are discussed. (C) 2005 European Federation of Internal Medicine. Published by Elsevier B.V All rights reserved.