Quantitative Ultrasound -: It is time to focus research efforts

被引:42
作者
Glueer, Claus-C. [1 ]
机构
[1] Univ Klinikum Schleswig Holstein, Radiol Diagnost Klin, Kiel, Germany
关键词
quantitative ultrasound; bone densitometry; bone strength; quality assurance; cost effectiveness; material properties; bone quality;
D O I
10.1016/j.bone.2006.07.014
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Quantitative Ultrasound (QUS) methods show great potential for refined assessment of bone strength. However, for widespread clinical acceptance, three issues have to be resolved: Will patients with low QUS readings benefit from approved osteoporosis medications? How can we ensure good quality of QUS measurements in daily clinical practice? How much added value does QUS bring to risk factor based case-finding strategies? When addressing these issues, differences among QUS approaches need to be recognized and vague and misleading terminology, e.g., regarding bone quality assessment, needs to be avoided. Innovations including assessment of material or micro-structural properties and direct QUS measurements at the proximal femur are likely to spark additional interest in pursuing QUS research. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码:9 / 13
页数:5
相关论文
共 27 条
[1]   Broadband ultrasound attenuation predicts fractures strongly and independently of densitometry in older women - A prospective study [J].
Bauer, DC ;
Gluer, CC ;
Cauley, JA ;
Vogt, TM ;
Ensrud, KE ;
Genant, HK ;
Black, DM .
ARCHIVES OF INTERNAL MEDICINE, 1997, 157 (06) :629-634
[2]   An in vitro study of the ultrasonic axial transmission technique at the radius: 1-MHz velocity measurements are sensitive to both mineralization and intracortical porosity [J].
Bossy, E ;
Talmant, M ;
Peyrin, F ;
Akrout, L ;
Cloetens, P ;
Laugier, P .
JOURNAL OF BONE AND MINERAL RESEARCH, 2004, 19 (09) :1548-1556
[3]   ULTRASOUND AND DENSITOMETRY OF THE CALCANEUS CORRELATE WITH THE FAILURE LOADS OF CADAVERIC FEMURS [J].
BOUXSEIN, ML ;
COURTNEY, AC ;
HAYES, WC .
CALCIFIED TISSUE INTERNATIONAL, 1995, 56 (02) :99-103
[4]   Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures - Results from the fracture intervention trial [J].
Cummings, SR ;
Black, DM ;
Thompson, DE ;
Applegate, WB ;
Barrett-Connor, E ;
Musliner, TA ;
Palermo, L ;
Prineas, R ;
Rubin, SM ;
Scott, JC ;
Vogt, T ;
Wallace, R ;
Yates, AJ ;
LaCroix, AZ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (24) :2077-2082
[5]   DXA of the hip and heel ultrasound but not densitometry of the fingers can discriminate female hip fracture patients from controls:: A comparison between four different methods [J].
Ekman, A ;
Michaëlsson, K ;
Petrén-Mallmin, M ;
Ljunghall, S ;
Mallmin, H .
OSTEOPOROSIS INTERNATIONAL, 2001, 12 (03) :185-191
[6]  
ENGELKE K, 2006, IN PRESS OSTEOPOROS
[7]   Treatment with alendronate prevents fractures in women at highest risk - Results from the fracture intervention trial [J].
Ensrud, KE ;
Black, DM ;
Palermo, L ;
Bauer, DC ;
BarrettConnor, E ;
Quandt, SA ;
Thompson, DE ;
Karpf, DB .
ARCHIVES OF INTERNAL MEDICINE, 1997, 157 (22) :2617-2624
[8]   Association of five quantitative ultrasound devices and bone densitometry with osteoporotic vertebral fractures in a population-based sample:: the OPUS study [J].
Glüer, CC ;
Eastell, R ;
Reid, DM ;
Felsenberg, D ;
Roux, C ;
Barkmann, R ;
Timm, W ;
Blenk, T ;
Armbrecht, G ;
Stewart, A ;
Clowes, J ;
Thomasius, FE ;
Kolta, S .
JOURNAL OF BONE AND MINERAL RESEARCH, 2004, 19 (05) :782-793
[9]   Quantitative ultrasound techniques for the assessment of osteoporosis: Expert agreement on current status [J].
Gluer, CC .
JOURNAL OF BONE AND MINERAL RESEARCH, 1997, 12 (08) :1280-1288
[10]  
GLUER CC, IN PRESS OSTEOPOROS