Effects of radiotherapy on parotid salivary sialochemistry in head and neck cancer patients

被引：2

作者：

Gupta, S. C. ^{[1
]}

Singla, Alok ^{[1
]}

Singh, Mangal ^{[1
]}

Thaliath, B. Paul ^{[1
]}

Geeta, Jaiswal ^{[1
]}

机构：

[1] MLN Med Coll, Dept ENT & Head & Neck Surg, Allahabad 211001, Uttar Pradesh, India

来源：

INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY | 2009年 / 61卷 / 04期

关键词：

Radiotherapy; Head and neck cancer; Parotid gland; Sodium; GLAND FUNCTION; RADIATION; XEROSTOMIA; SECRETION; FLORA;

D O I：

10.1007/s12070-009-0084-7

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

To determine the effects of high dose irradiation on parotid salivary sodium and pH concentration at subsequent duration of 1.5, 3 and 6 months following radiotherapy. Eighty parotid glands of head and neck cancer patients were irradiated with mean dose of 66 Gy. The stimulated parotid flow (PF) was collected by a cannulation of Stenson's duct followed by analysis of sodium (PF sodium) by Easylyte Sodium/Potassium auto analyzer and pH by litmus narrow band pH paper. A steep elevation of PF sodium was found in post-RT period after 1.5 months of starting RT followed by gradual increase up to 6 months and pH changed towards acidity. A high dose of 66 Gy causes irreversible damage to parotid salivary duct system.

引用

页码：286 / 290

页数：5

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