Antihyperlipidemic Compounds from the Fruit of Piper longum L.

被引：49

作者：

Jin, Zhuang ^{[1
]}

Borjihan, Gereltu ^{[1
]}

Zhao, Ruiguo ^{[1
]}

Sun, Zhaorigetu ^{[1
]}

Hammond, Gerald B. ^{[2
]}

Uryu, Toshiyuki ^{[3
]}

机构：

[1] Inner Mongolia Univ, Inst Macromol Chem & Mongolian Med, Hohhot 010021, Peoples R China

[2] Univ Louisville, Dept Chem, Louisville, KY 40292 USA

[3] Teikyo Univ Sci & Technol, Yamanashi 4090193, Japan

来源：

PHYTOTHERAPY RESEARCH | 2009年 / 23卷 / 08期

关键词：

antihyperlipidemic activity; Piper longum L; piperlonguminine; piperine; piperonaline; RATS; REDUCTASE;

D O I：

10.1002/ptr.2630

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A bioassay-guided isolation of an ethanol extract of the fruit of Piper longum L. yielded piperlonguminine, piperine and pipernonaline, as the main antihyperlipidemic constituents. They exhibit appreciable antihyperlipidemic activity in vivo, which is comparable to that of the commercial antihyperlipidemic drug, simvastatin. Copyright (C) 2009 John Wiley & Sons, Ltd.

引用

页码：1194 / 1196

页数：3

共 50 条

[1] DETERMINATION OF BIOACTIVE COMPOUNDS FROM PIPER LONGUM L. BY USING HP-LC ANALYSIS
Manjusha, S.
Parameswaran, N. K.
Malar, R. Senthil
INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 5 (04): : 2942 - 2945
[2] Antiplatelet effects of acidamides isolated from the fruits of Piper longum L.
Park, B. -S.
Son, D. -J.
Park, Y. -H.
Kim, T. W.
Lee, S. -E.
PHYTOMEDICINE, 2007, 14 (12) : 853 - 855
[3] Screening of antidiabetic and antihyperlipidemic potential of oil from Piper longum and piperine with their possible mechanism
Kumar, Suresh
Sharma, Sunil
Vasudeva, Neeru
EXPERT OPINION ON PHARMACOTHERAPY, 2013, 14 (13) : 1723 - 1736
[4] Antiinflammatory Activity of Piper longum Fruit Oil
Kumar, A.
Panghal, S.
Mallapur, S. S.
Kumar, M.
Ram, Veerma
Singh, B. K.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2009, 71 (04) : 454 - U179
[5] Piperine production by endophytic fungus Periconia sp isolated from Piper longum L.
Verma, Vijay C.
Lobkovsky, Emil
Gange, Alan C.
Singh, Santosh K.
Prakash, Satya
JOURNAL OF ANTIBIOTICS, 2011, 64 (06) : 427 - 431
[6] Identification of Piper longum L. from Different Areas by FTIR and HPLC Fingerprint Methods
Zhang Hui-wen
Song Xiao-ling
Shi Song-li
Zhang Sha-sha
Liang Yue
Wang Huan-yun
SPECTROSCOPY AND SPECTRAL ANALYSIS, 2020, 40 (01) : 174 - 178
[7] Amide and phenylpropanoid glycosides from the fruits of Piper longum L. and their anti-inflammatory activity
Gou, Guanghui
Liu, Liu
Bao, Wenli
Li, Jun
Aisa, Haji Akber
JOURNAL OF NATURAL MEDICINES, 2025, : 686 - 694
[8] Piperine production by endophytic fungus Periconia sp. Isolated from Piper longum L.
Vijay C Verma
Emil Lobkovsky
Alan C Gange
Santosh K Singh
Satya Prakash
The Journal of Antibiotics, 2011, 64 : 427 - 431
[9] Dimeric Amide Alkaloid Enantiomers from Piper longum L. with Anti-Inflammatory and Antidiabetic Effects
Gou, Guanghui
Liu, Liu
Bao, Wenli
Li, Jun
Aisa, Haji Akber
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2025, 73 (11) : 6955 - 6969
[10] Anti-inflammatory effect of Piper longum L. fruit methanolic extract on lipopolysaccharide-treated RAW 264.7 murine macrophages
Phan, Uyen Thi Tu
Nguyen, Hai Dang
Nguyen, Thi Kieu Oanh
Tran, Tuan Hiep
Le, Thanh Huong
Tran, Thi Thu Phuong
HELIYON, 2024, 10 (04)

← 1 2 3 4 5 →