Therapeutic Inhibition of Complement: Well Worth the Risk

被引：18
作者：
Barnum, Scott R. [1 ,2 ]
机构：
[1] Univ Alabama Birmingham, Dept Microbiol, Birmingham, AL 35294 USA
[2] Univ Alabama Birmingham, Dept Neurol, UAB Stn, Birmingham, AL 35294 USA
来源：
TRENDS IN PHARMACOLOGICAL SCIENCES | 2017年 / 38卷 / 06期
关键词：
ECULIZUMAB;
D O I：
10.1016/j.tips.2017.03.009
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Complement is an integral part of the immune system and protects against infection. Complement-mediated immunopathology in many autoimmune diseases and syndromes has led to the therapeutic targeting of complement and to questions around the safety of complement inhibition. Here; I examine and clarify the risks associated with complement therapeutics.
引用
收藏
页码：503 / 505
页数：3
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