Becoming more oneself? Changes in personality following DBS treatment for psychiatric disorders: Experiences of OCD patients and general considerations

被引:66
作者
de Haan, Sanneke [1 ,2 ]
Rietveld, Erik [3 ,4 ,5 ]
Stokhof, Martin [5 ]
Denys, Damiaan [3 ,6 ]
机构
[1] Humboldt Univ, Berlin Sch Mind & Brain, Berlin, Germany
[2] Radboud Univ Nijmegen, Fac Philosophy Theol & Religious Studies, Nijmegen, Netherlands
[3] Univ Amsterdam, Acad Med Ctr, Dept Psychiat, Amsterdam, Netherlands
[4] Univ Amsterdam, Amsterdam Brain & Cognit, Amsterdam, Netherlands
[5] Univ Amsterdam, Dept Philosophy, Inst Log Language & Computat, Amsterdam, Netherlands
[6] Royal Netherlands Acad Arts & Sci, Netherlands Inst Neurosci, Amsterdam, Netherlands
关键词
DEEP BRAIN-STIMULATION; SUBTHALAMIC NUCLEUS STIMULATION; PARKINSONS-DISEASE; AUTHENTICITY; NEUROSURGERY; ACCUMBENS; ENHANCEMENT; PERCEPTIONS; IMPULSIVITY; INCREASES;
D O I
10.1371/journal.pone.0175748
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Does DBS change a patient's personality? This is one of the central questions in the debate on the ethics of treatment with Deep Brain Stimulation ( DBS). At the moment, however, this important debate is hampered by the fact that there is relatively little data available concerning what patients actually experience following DBS treatment. There are a few qualitative studies with patients with Parkinson's disease and Primary Dystonia and some case reports, but there has been no qualitative study yet with patients suffering from psychiatric disorders. In this paper, we present the experiences of 18 patients with Obsessive-Compulsive Disorder (OCD) who are undergoing treatment with DBS. We will also discuss the inherent difficulties of how to define and assess changes in personality, in particular for patients with psychiatric disorders. We end with a discussion of the data and how these shed new light on the conceptual debate about how to define personality.
引用
收藏
页数:27
相关论文
共 69 条
[1]   Deep brain stimulation for refractory obsessive-compulsive disorder [J].
Abelson, JL ;
Curtis, GC ;
Sagher, O ;
Albucher, RC ;
Harrigan, M ;
Taylor, SF ;
Martis, B ;
Giordani, B .
BIOLOGICAL PSYCHIATRY, 2005, 57 (05) :510-516
[2]  
Agid Y, 2006, J NEURAL TRANSM-SUPP, P409
[3]  
[Anonymous], 2011, AJOB NEUROSCIENCE, DOI DOI 10.1080/21507740.2010.537535
[4]  
[Anonymous], 2011, AJOB NEUROSCIENCE, DOI DOI 10.1080/21507740.2010.533151
[5]  
[Anonymous], DIAGNOSTIC AND STATI
[6]  
[Anonymous], 2013, FRONT HUM NEUROSCI
[7]   "I Am Who I Am": On the Perceived Threats to Personal Identity from Deep Brain Stimulation [J].
Baylis, Francoise .
NEUROETHICS, 2013, 6 (03) :513-526
[8]   Deep Brain Stimulation of the Ventral Anterior Limb of the Internal Capsule for Treatment-Resistant Depression A Randomized Clinical Trial [J].
Bergfeld, Isidoor O. ;
Mantione, Mariska ;
Hoogendoorn, Mechteld L. C. ;
Ruhe, Henricus G. ;
Notten, Peter ;
van Laarhoven, Jan ;
Visser, Ieke ;
Figee, Martijn ;
de Kwaasteniet, Bart P. ;
Horst, Ferdinand ;
Schene, Aart H. ;
van den Munckhof, Pepijn ;
Beute, Guus ;
Schuurman, Rick ;
Denys, Damiaan .
JAMA PSYCHIATRY, 2016, 73 (05) :456-464
[9]   Ethical brain stimulation - neuroethics of deep brain stimulation in research and clinical practice [J].
Clausen, Jens .
EUROPEAN JOURNAL OF NEUROSCIENCE, 2010, 32 (07) :1152-1162
[10]  
de Haan S, 2015, FREE WILL AND THE BR