Nickel-Catalyzed Cycloaddition of Salicylic Acid Ketals to Alkynes via Elimination of Ketones

被引：48

作者：

Ooguri, Akihiro ^{[1
]}

Nakai, Kenichiro ^{[1
]}

Kurahashi, Takuya ^{[1
]}

Matsubara, Seijiro ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Kyoto 6158510, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 37期

关键词：

ARYLBORONIC ACIDS; ENONES; CYCLIZATIONS; ALKENES; DIYNES; BOND;

D O I：

10.1021/ja904068p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An intermolecular nickel-catalyzed addition reaction has been developed where salicylic acid ketals react with alkynes to afford substituted chromones. A mechanistic rationale is proposed, implying beta-elimination of ketone from ring strained seven-membered nickelacycle to generate a five-membered oxa-nickelacycle intermediate.

引用

页码：13194 / 13195

页数：2

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