Radiation Grafting of Acrylic Acid/N-Vinyl Pyrrolidone Binary Mixture Onto Poly(ethylene terephthalate) Fabric and Growth of Human Mesenchymal Stem Cell

被引：10

作者：

Gupta, Bhuvanesh ^{[1
]}

Grover, Navdeep ^{[1
,2
]}

Mohanty, Sujata ^{[3
]}

Jain, Krishan Gopal ^{[3
]}

Singh, Harpal ^{[2
]}

机构：

[1] Indian Inst Technol, Dept Text Technol, New Delhi 110016, India

[2] Indian Inst Technol, Ctr Biomed Engn, New Delhi 110016, India

[3] All India Inst Med Sci, Stem Cell Facil, New Delhi 110029, India

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 2010年 / 115卷 / 01期

关键词：

PET knitting; acrylic acid (AA); N-vinyl pyrrolidone (NVP); radiation; grafting; HYDROPHILIC PLASMA POLYMERS; HUMAN ENDOTHELIAL-CELLS; SURFACE MODIFICATION; N-VINYLPYRROLIDONE; ANTIBACTERIAL ACTIVITY; CRAFT POLYMERIZATION; POLYESTER FIBERS; METALLIC SALT; FILMS; POLYPROPYLENE;

D O I：

10.1002/app.30915

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Radiation grafting of acrylic acid (AA)/N-vinyl pyrrolidone (NVP) binary mixture onto poly(ethylene terephthalate) (PET) knittings was investigated by pre-irradiation technique. The influence of the grafting conditions, such as monomer composition, reaction temperature, and the effect of storage time with temperature after irradiation on the degree of grafting was determined. ATR-FTIR spectroscopy analysis of the grafted knittings confirmed the existence of amide group of NVP in the knittings. The concentration of peroxides and effect of storage time on peroxide concentration were also determined by 2,2-Diphenyl-1-picrylhydrazyl at different temperatures. There was an increase in surface roughness of grafted PET in comparison to virgin PET as determined by atomic force microscopy and scanning electron microscopy. The grafted knittings were subsequently immobilized with collagen Type I which was further apt for the study of growth and morphology of human mesenchymal stem cell (hMSC). The immobilization of collagen on PET knittings has provided an excellent surface for the growth of hMSCs. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 115: 116-126, 2010

引用

页码：116 / 126

页数：11

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