Effects of bacterial glyceroglycolipid M874B on growth and TPA-induced differentiation of HL60 cells

被引：7
作者：
Matsufuji, M
Nagamatsu, Y
Yoshimoto, A
机构：
[1] Mercian Corp, Cent Res Labs, Fujisawa, Kanagawa 2510057, Japan
[2] Hiroshima Univ, Fac Appl Biol Sci, Higashihiroshima 7398526, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2000年 / 64卷 / 06期
关键词：
glyceroglycolipid; oxygen radical scavenger; HL60; cell; differentiation;
D O I：
10.1271/bbb.64.1302
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bacterial monogalactosyldiacylglycerol M874B (MGDAG), which protects against oxygen radicals, was found to increase the growth of the human promyelocytic leukemia cell HL60 when added to the cell culture, but suppresses the 12-O-tetradecanoyl phorbol-13-acetate-induced differentiation. Analogous MGDAG, S365B had weak, but similar effects. These activities were not observed with analogous plant glyceroglycolipids and diacylglycerol.
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页码：1302 / 1304
页数：3
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