The University of Michigan Honest Broker: A Web-based Service for Clinical and Translational Research and Practice

被引：28

作者：

Boyd, Andrew D. ^{[1
,3
,7
]}

Saxman, Paul R. ^{[6
]}

Hunscher, Dale A. ^{[6
]}

Smith, Kevin A. ^{[6
]}

Morris, Timothy D. ^{[2
]}

Kaston, Michelle ^{[1
]}

Bayoff, Frederick ^{[1
]}

Rogers, Bruce ^{[4
]}

Hayes, Pamela ^{[6
]}

Rajeev, Namrata ^{[6
]}

Kline-Rogers, Eva ^{[4
]}

Eagle, Kim ^{[4
,5
]}

Clauw, Daniel ^{[5
,6
]}

Greden, John F. ^{[1
,3
]}

Green, Lee A. ^{[2
]}

Athey, Brian D. ^{[1
,3
]}

机构：

[1] Univ Michigan, Dept Psychiat, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Dept Family Med, Ann Arbor, MI 48109 USA

[3] Univ Michigan, Depress Ctr, Ann Arbor, MI 48109 USA

[4] Univ Michigan, Ctr Cardiovasc, Ann Arbor, MI 48109 USA

[5] Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA

[6] Michigan Inst Clin & Hlth Res, Ann Arbor, MI USA

[7] Univ Illinois, Dept Biomed & Hlth Informat Sci, Chicago, IL USA

来源：

JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION | 2009年 / 16卷 / 06期

基金：

美国国家卫生研究院;

关键词：

CARDIOVASCULAR-DISEASE; PATIENT-CARE; DEPRESSION; PRIVACY;

D O I：

10.1197/jamia.M2985

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

For the success of clinical and translational science, a seamless interoperation is required between clinical and research information technology. Addressing this need, the Michigan Clinical Research Collaboratory (MCRC) was created. The MCRC employed a standards-driven Web Services architecture to create the U-M Honest Broker, which enabled sharing of clinical and research data among medical disciplines and separate institutions. Design objectives were to facilitate sharing of data, maintain a master patient index (MPI), deidentification of data, and routing data to preauthorized destination systems for use in clinical care, research, or both. This article describes the architecture and design of the U-M HB system and the successful demonstration project. Seventy percent of eligible patients were recruited for a prospective study examining the correlation between interventional cardiac catheterizations and depression. The U-M Honest Broker delivered on the promise of using structured clinical knowledge shared among providers to help clinical and translational research. J Am Med Inform Assoc. 2009;16:784-791. DOI 10.11.97/jamia.M2985.

引用

页码：784 / 791

页数：8

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