A metabolic switch in proteasome inhibitor-resistant multiple myeloma ensures higher mitochondrial metabolism, protein folding and sphingomyelin synthesis

被引：53

作者：

Besse, Lenka ^{[1
]}

Besse, Andrej ^{[1
]}

Mendez-Lopez, Max ^{[1
]}

Vasickova, Katerina ^{[2
]}

Sedlackova, Miroslava ^{[2
]}

Vanhara, Petr ^{[2
]}

Kraus, Marianne ^{[1
]}

Bader, Jurgen ^{[1
]}

Ferreira, Renan B. ^{[3
]}

Castellano, Ronald K. ^{[3
,4
]}

Law, Brian K. ^{[4
,5
]}

Driessen, Christoph ^{[1
]}

机构：

[1] St Gallen Cantonal Hosp, Dept Hematol & Oncol, Expt Oncol & Hematol, St Gallen, Switzerland

[2] Masaryk Univ, Dept Histol & Embryol, Fac Med, Brno, Czech Republic

[3] Univ Florida, Dept Chem, Gainesville, FL 32611 USA

[4] Univ Florida, UF Hlth Canc Ctr, Gainesville, FL USA

[5] Univ Florida, Dept Pharmacol & Therapeut, Gainesville, FL USA

来源：

HAEMATOLOGICA | 2019年 / 104卷 / 09期

基金：

瑞士国家科学基金会;

关键词：

REDOX; BORTEZOMIB; CELLS;

D O I：

10.3324/haematol.2018.207704

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：5

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