Methylation and expression of the p1 61NK4A tumor suppressor gene in multiple myeloma

被引：21

作者：

Dib, Amel ^{[1
]}

Barlogie, Bart ^{[1
]}

Shaughnessy, John D., Jr. ^{[1
]}

Kuehl, Michael ^{[1
]}

机构：

[1] USN Hosp, Natl Canc Inst, Bethesda, MD 20889 USA

来源：

BLOOD | 2007年 / 109卷 / 03期

关键词：

D O I：

10.1182/blood-2006-09-049510

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1337 / 1338

页数：2

共 10 条

[1] Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma [J].

Bergsagel, PL ;

Kuehl, WM ;

Zhan, FH ;

Sawyer, J ;

Barlogie, B ;

Shaughnessy, J .

BLOOD, 2005, 106 (01) :296-303

[2] Germline CDKN2A mutation implicated in predisposition to multiple myeloma [J].

Dilworth, D ;

Liu, L ;

Stewart, AK ;

Berenson, JR ;

Lassam, N ;

Hogg, D .

BLOOD, 2000, 95 (05) :1869-1871

[3] Tumor suppressor p16 methylation in multiple myeloma:: biological and clinical implications [J].

Gonzalez-Paz, Natalia ;

Chng, Wee J. ;

McClure, Rebecca F. ;

Blood, Emily ;

Oken, Martin M. ;

Van Ness, Brian ;

James, C. David ;

Kurtin, Paul J. ;

Henderson, Kimberly ;

Ahmann, Gregory J. ;

Gertz, Morie ;

Lacy, Martha ;

Dispenzieri, Angela ;

Greipp, Philip R. ;

Fonseca, Rafael .

BLOOD, 2007, 109 (03) :1228-1232

[4] p16INK4a and p15INK4b gene methylations in plasma cells from monoclonal gammopathy of undetermined significance [J].

Guillerm, G ;

Gyan, E ;

Wolowiec, D ;

Facon, T ;

Avet-Loiseau, H ;

Kuliczkowski, K ;

Bauters, F ;

Fenaux, P ;

Quesnel, B .

BLOOD, 2001, 98 (01) :244-246

[5]

Holst CR, 2003, CANCER RES, V63, P1596

[6] Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma [J].

Hurt, EM ;

Wiestner, A ;

Rosenwald, A ;

Shaffer, AL ;

Campo, E ;

Grogan, T ;

Bergsagel, PL ;

Kuehl, WM ;

Staudt, LM .

CANCER CELL, 2004, 5 (02) :191-199

[7] RB and cyclin dependent kinase pathways: defining a distinction between RB and p16 loss in lung cancer [J].

Kaye, FJ .

ONCOGENE, 2002, 21 (45) :6908-6914

[8]

Mateos M V, 2001, Hematol J, V2, P146, DOI 10.1038/sj.thj.6200084

[9] Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia [J].

Uchida, T ;

Kinoshita, T ;

Ohno, T ;

Ohashi, H ;

Nagai, H ;

Saito, H .

LEUKEMIA, 2001, 15 (01) :157-165

[10] Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibility [J].

Zhang, SL ;

DuBois, W ;

Ramsay, ES ;

Bliskovski, V ;

Morse, HC ;

Taddesse-Heath, L ;

Vass, WC ;

DePinho, RA ;

Mock, BA .

MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (01) :310-318

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