Gap junctions in the eye: evidence for heteromeric, heterotypic and mixed-homotypic interactions

被引:36
作者
Vaney, DI [1 ]
Weiler, R
机构
[1] Univ Queensland, Vis Touch & Hearing Res Ctr, Brisbane, Qld 4072, Australia
[2] Univ Oldenburg, D-26111 Oldenburg, Germany
关键词
connexin; lens; ciliary body; retina;
D O I
10.1016/S0165-0173(99)00070-3
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Some of the best evidence that different types of gap junction proteins (connexins) interact with each other in vivo has been found in the eye. This review focuses on three diverse ocular tissues that may contain heterotypic or heteromeric gap junction channels. Each of the tissues uses gap junctions in a superlative fashion: The crystalline lens has an exceptionally high density of gap junctions; the ciliary body expresses a surprising variety of connexins; the neural retina shows remarkable specificity in the patterns of intercellular coupling. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:115 / 120
页数:6
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