Upregulation of hepatic cholesterol 27-hydroxylase (CYP27) activity and normal levels of hepatic cholesterol synthesis in cholesterol 7A-hydroxylase(CYP7A1) gene knockout mice.

被引：3
|
作者：
Shefer, S
Erickson, SK
Lear, SR
Batta, AK
Salen, G
机构：
[1] Univ Med & Dent New Jersey, Newark, NJ 07103 USA
[2] Univ Calif San Francisco, San Francisco, CA 94143 USA
[3] VAMC, San Francisco, CA USA
[4] VAMC E Orange, E Orange, NJ USA
来源：
GASTROENTEROLOGY | 2000年 / 118卷 / 04期
关键词：
D O I：
10.1016/S0016-5085(00)86142-9
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
1168
引用
收藏
页码：A998 / A998
页数：1
相关论文
共 50 条
  • [1] Species differences in the response of cholesterol 7α-hydroxylase (CYP7) and sterol 27-hydroxylase (CYP27) to excess cholesterol.
    Pandak, WM
    Heuman, DM
    Vlahcevic, ZR
    HEPATOLOGY, 1998, 28 (04) : 379A - 379A
  • [2] Effect of cholesterol 27-hydroxylase (CYP27A) gene knockout on cholesterol and bile acid homeostasis in mice.
    Erickson, SK
    Shefer, S
    Lear, SR
    Batta, AK
    Maeda, N
    Salen, G
    HEPATOLOGY, 2000, 32 (04) : 388A - 388A
  • [3] Bile acids and FXR represses cholesterol 7A-hydroxylase (CYP7A1), sterol 12A-hydroxylase (CYP8B1) and sterol 27-hydroxylase (CYP27A1), but not oxysterol 7A-hydroxylase (CYP7B1) gene transcription.
    Chiang, JY
    Chen, W
    Zheng, M
    Wu, Z
    Kimmel, R
    Stroup, D
    GASTROENTEROLOGY, 2000, 118 (04) : A1006 - A1006
  • [4] Dietary cholesterol fails to stimulate the human cholesterol 7α-hydroxylase gene (CYP7A1) in transgenic mice.
    Agellon, LB
    Drover, VAB
    Cheema, SK
    Gbaguidi, GF
    Walsh, A
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (23) : 20131 - 20134
  • [5] Role of Cholesterol 7α-Hydroxylase (CYP7A1) in Nutrigenetics and Pharmacogenetics of Cholesterol Lowering
    Jaroslav A. Hubacek
    Dagmar Bobkova
    Molecular Diagnosis & Therapy, 2006, 10 : 93 - 100
  • [6] Role of cholesterol 7α-hydroxylase (CYP7A1) in nutrigenetics and pharmacogenetics of cholesterol lowering
    Hubacek, Jaroslav A.
    Bobkova, Dagmar
    MOLECULAR DIAGNOSIS & THERAPY, 2006, 10 (02) : 93 - 100
  • [7] Frontal lobe dementia with abnormal cholesterol metabolism and heterozygous mutation in sterol 27-hydroxylase gene (CYP27)
    Sugama, S
    Kimura, A
    Chen, W
    Kubota, S
    Seyama, Y
    Taira, N
    Eto, Y
    JOURNAL OF INHERITED METABOLIC DISEASE, 2001, 24 (03) : 379 - 392
  • [8] Structural aspects of bile acids involved in the regulation of cholesterol 7a-hydroxylase and sterol 27-hydroxylase
    Twisk, J.
    Hoekman, M. F. M.
    Muller, L. M.
    Iida, T.
    Numerische Mathematik, 6985
  • [9] Cholesterol 7α-hydroxylase (CYP7A1) plays a critical role in preventing hepatic inflammation and fibrosis
    Liu, Hailiang
    Ferrell, Jessica
    Boehme, Shannon
    Chiang, John
    FASEB JOURNAL, 2016, 30
  • [10] Expression of sterol 27-hydroxylase (CYP27A1) enhances cholesterol efflux
    Escher, G
    Krozowski, Z
    Croft, KD
    Sviridov, D
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (13) : 11015 - 11019
12345