Circulating MicroRNAs as Potential Biomarkers of Atrial Fibrillation

被引：33

作者：

Gomes da Silva, Ananilia Medeiros ^{[1
]}

Goes de Araujo, Jessica Nayara ^{[1
]}

Costa de Freitas, Renata Caroline ^{[1
]}

Silbiger, Vivian Nogueira ^{[1
]}

机构：

[1] Univ Fed Rio Grande do Norte, Dept Clin & Toxicol Analyses, Natal, RN, Brazil

来源：

BIOMED RESEARCH INTERNATIONAL | 2017年 / 2017卷

关键词：

CATHETER ABLATION; EXPRESSION; PLATELETS; FAILURE; PROFILE; MIRNAS;

D O I：

10.1155/2017/7804763

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Atrial fibrillation (AF) is the most common supraventricular arrhythmia in the population. MicroRNAs (small endogenous noncoding RNAs) are attractive candidates as biomarkers for AF, especially considering that miRNAs are stable and are detected within easily accessible biofluids such as blood. In this review, we selected twelve studies (2012 to 2016) that were classified according to the sample type. We aimed to provide an overview of the role of circulating miRNAs in AF and to discuss the variability of the results, seeking to improve the perspective of the use of miRNAs as potential noninvasive biomarkers for this heart disease.

引用

页数：7

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