Emergencies caused by pheochromocytoma, neuroblastoma, or ganglioneuroma

被引:43
作者
Brouwers, Frederieke M.
Eisenhofer, Graeme
Lenders, Jacques W. M.
Pacak, Karel
机构
[1] NICHHD, Sect Med Neuroendocrinol, Reprod Biol & Med Branch, Bethesda, MD 20892 USA
[2] NINDS, Clin Neurocardiol Sect, NIH, Bethesda, MD 20892 USA
[3] Radboud Univ Nijmegen, Dept Internal Med, Div Gen Internal Med, Med Ctr, NL-6500 HB Nijmegen, Netherlands
关键词
D O I
10.1016/j.ecl.2006.09.014
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pheochromocytoma may lead to important emergency situations, ranging from cardiovascular emergencies to acute abdomen and multiorgan failure. It is vital to think about this disease in any emergency situation when conventional therapy fails to achieve control or symptoms occur that do not fit the initial diagnosis. The importance of keeping this diagnosis in mind is underscored by the fact that, in 50% of pheochromocytoma patients, the diagnosis is initially overlooked. Two other tumors of the sympathetic nervous system, neuroblastoma and ganglioneuroma, are less commonly associated with emergency conditions. If they occur, they are often linked to catecholamine excess, paraneoplastic phenomena, or local tumor mass effect.
引用
收藏
页码:699 / +
页数:27
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