Individualized Homeopathic Medicines in Stage I Essential Hypertension: A Double-Blind, Randomized, Placebo-Controlled Pilot Trial

被引：3

作者：

Sadhukhan, Satarupa ^{[1
]}

Singh, Subhas ^{[2
]}

Michael, James ^{[1
]}

Misra, Pankhuri ^{[3
]}

Parewa, Maneet ^{[4
]}

Nath, Arunava ^{[1
]}

Magotra, Nitin ^{[1
]}

Kundu, Nivedita ^{[1
]}

Basu, Anamika ^{[5
]}

Ali, Sk Swaif ^{[5
]}

Koley, Munmun ^{[6
]}

Saha, Subhranil ^{[7
]}

机构：

[1] Natl Inst Homoeopathy, Dept Organon Med & Homoeopath Philosophy, Kolkata, India

[2] Natl Inst Homoeopathy, Kolkata, India

[3] Natl Inst Homoeopathy, Dept Mat Med, Kolkata, India

[4] Natl Inst Homoeopathy, Dept Repertory, Kolkata, India

[5] Mahesh Bhattacharyya Homoeopath Med Coll & Hosp, Dept Practice Med, Govt West Bengal, Howrah, India

[6] State Natl Homoeopath Med Coll & Hosp, Dept Organon Med & Homoeopath Philosophy, Govt Uttar Pradesh, Lucknow, Uttar Pradesh, India

[7] DN Homoeopath Med Coll & Hosp, Dept Repertory, Govt West Bengal, Kolkata, India

来源：

JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE | 2021年 / 27卷 / 06期

关键词：

essential hypertension; homeopathy; placebo; pilot trial; randomized controlled trial; BLOOD-PRESSURE; PUBLICATION; DRUG;

D O I：

10.1089/acm.2020.0222

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Objective: The present study assessed the feasibility of a definitive placebo-controlled trial for evaluating individualized homeopathy (IH) in stage I hypertension (HTN). Design: Double-blind, randomized (IH: 34, placebo: 34), placebo-controlled, parallel arms, pilot trial. Settings/Location: National Institute of Homoeopathy, India. Subjects: Patients suffering from stage I HTN. Interventions: IH and identical-looking placebo. Outcome measures: Feasibility issues, blood pressure (BP) and Measure Yourself Medical Outcome Profile-2 (MYMOP-2) were assessed for 6 months. Results: The recruitment and retention rates were 44.4% and 85.3%, respectively. Group differences were seemingly higher in the IH group than in the placebo group. Conclusions: Despite challenges in recruitment, an adequately powered efficacy trial appears feasible in the future.

引用

页码：515 / 521

页数：7

共 22 条

[1] Sample-Size Planning for More Accurate Statistical Power: A Method Adjusting Sample Effect Sizes for Publication Bias and Uncertainty [J].

Anderson, Samantha F. ;

Kelley, Ken ;

Maxwell, Scott E. .

PSYCHOLOGICAL SCIENCE, 2017, 28 (11) :1547-1562

[2]

Camargo LADB., 1988, REV HOMEOPATIA SAO P, V53, P132

[3]

Central Council for Research in Homoeopathy., 2009, Qarabadeen-e-Qadri

[4] Minimal Clinically Important Difference (MCID)-Adding Meaning to Statistical Inference [J].

Chan, Linda S. .

AMERICAN JOURNAL OF PUBLIC HEALTH, 2013, 103 (11) :E24-E25

[5]

Consoli AM., 1987, BR HOM J, V76, P114

[6] Reporting data on homeopathic treatments (RedHot): a supplement to CONSORT [J].

Dean, M. E. ;

Coulter, M. K. ;

Fisher, P. ;

Jobst, K. ;

Walach, H. .

HOMEOPATHY, 2007, 96 (01) :42-45

[7] CONSORT 2010 statement: extension to randomised pilot and feasibility trials [J].

Eldridge, Sandra M. ;

Chan, Claire L. ;

Campbell, Michael J. ;

Bond, Christine M. ;

Hopewell, Sally ;

Thabane, Lehana ;

Lancaster, Gillian A. .

BMJ-BRITISH MEDICAL JOURNAL, 2016, 355

[8]

Fernez-Arguelles R., 1999, B MEXICANO HOM, V32, P42

[9]

HITZENBERGER G, 1982, WIEN KLIN WOCHENSCHR, V94, P665

[10]

Hitzenberger G, 2005, WIEN MED WOCHENSCHR, V155, P392, DOI 10.1007/s10354-005-0204-2

← 1 2 3 →