Prevalence and Genotypes of Helicobacter pylori in Gastric Biopsy Specimens from Patients with Gastroduodenal Pathologies in the Cukurova Region of Turkey

被引：23

作者：

Nagiyev, Togrul ^{[1
]}

Yula, Erkan ^{[1
]}

Abayli, Bahri ^{[2
]}

Koksal, Fatih ^{[1
]}

机构：

[1] Cukurova Univ, Fac Med, Dept Microbiol, Adana, Turkey

[2] Adana Cukurova Govt Hosp, Dept Gastroenterol, Adana, Turkey

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2009年 / 47卷 / 12期

关键词：

DISTINCT DIVERSITY; DUODENAL-ULCER; VACA GENOTYPES; PEPTIC-ULCER; CAGA; STRAINS; DISEASE; HETEROGENEITY; ICEA; ASSOCIATION;

D O I：

10.1128/JCM.00605-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The effects of Helicobacter pylori genotypes on clinical prognosis in the Cukurova region of Turkey were investigated by PCR. The prevalence of type I strains carrying the s1c allele, unlike in neighboring regions and countries, was found to be significantly higher in patients with gastritis and/or gastric ulcers (P = 0.001), and that of type I strains carrying the s1a allele was found to be significantly higher in patients with duodenal ulcers (P < 0.001). The cagA gene was strongly associated with the more virulent vacA genotypes (P < 0.001).

引用

页码：4150 / 4153

页数：4

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