Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup

被引：1108

作者：

Chawla, Lakhmir S. ^{[1
]}

Bellomo, Rinaldo ^{[2
]}

Bihorac, Azra ^{[3
]}

Goldstein, Stuart L. ^{[4
]}

Siew, Edward D. ^{[5
]}

Bagshaw, Sean M. ^{[6
]}

Bittleman, David ^{[7
]}

Cruz, Dinna ^{[8
]}

Endre, Zoltan ^{[9
,10
]}

Fitzgerald, Robert L.

Forni, Lui ^{[11
]}

Kane-Gill, Sandra L. ^{[12
]}

Hoste, Eric ^{[13
]}

Koyner, Jay ^{[14
]}

Liu, Kathleen D. ^{[15
]}

Macedo, Etienne

Mehta, Ravindra

Murray, Patrick ^{[16
]}

Nadim, Mitra ^{[17
]}

Ostermann, Marlies ^{[18
]}

Palevsky, Paul M. ^{[19
,20
]}

Pannu, Neesh ^{[21
]}

Rosner, Mitchell ^{[22
]}

Wald, Ron ^{[23
,24
]}

Zarbock, Alexander ^{[25
]}

Ronco, Claudio ^{[26
]}

Kellum, John A. ^{[27
]}

机构：

[1] Vet Affairs Med Ctr, Dept Med, 50 Irving St, Washington, DC 20310 USA

[2] Monash Univ, Australian & New Zealand Intens Care Res Ctr, Clayton, Vic 3800, Australia

[3] Univ Florida, Dept Med, Gainesville, FL 32611 USA

[4] Cincinnati Childrens Hosp Med Ctr, Div Nephrol & Hypertens, Cincinnati, OH 45229 USA

[5] Vanderbilt Univ, Sch Med, Div Nephrol & Hypertens, Nashville, TN USA

[6] Univ Alberta, Fac Med & Dent, Div Crit Care Med, Edmonton, AB T6G 2M7, Canada

[7] Univ Calif San Diego, Dept Med, San Diego, CA USA

[8] Univ Calif San Diego, UCSD Med Ctr, San Diego, CA USA

[9] Univ New South Wales, Prince Wales Hosp, Dept Nephrol, Kensington, NSW, Australia

[10] Univ New South Wales, Sch Clin, Kensington, NSW, Australia

[11] Surrey Cty Hosp, Surrey, England

[12] Univ Pittsburgh, Sch Pharm, Pittsburgh, PA 15260 USA

[13] Univ Ghent, Ghent Univ Hosp, Intens Care Unit, Ghent, Belgium

[14] Univ Chicago, Dept Med, Chicago, IL USA

[15] Univ Calif San Francisco, Dept Med & Anesthesia, Divi Nephrol & Crit Care, San Francisco, CA 94143 USA

[16] Uni Coll Dublin, UCD Hlth Sci Ctr, Dublin, Ireland

[17] Univ Southern California, Keck Sch Med, Dept Med, Div Nephrol, Los Angeles, CA USA

[18] Guys & St Thomas NHS Fdn Hosp, Dept Intens Care, Westminster, England

[19] VA Pittsburgh Healthcare Syst, Renal Sect, Pittsburgh, PA USA

[20] Univ Pittsburgh, Renal Electrolyte Div, Pittsburgh, PA USA

[21] Univ Alberta, Fac Med & Dent, Div Crit Care Med, Edmonton, AB T6G 2M7, Canada

[22] Univ Virginia, Div Nephrol, Charlottesville, VA 22903 USA

[23] St Michaels Hosp, Div Nephrol, Toronto, ON, Canada

[24] Univ Toronto, Toronto, ON, Canada

[25] Univ Hosp Munster, Munster, Germany

[26] San Bortolo Hosp, Int Renal Res Inst Vicenza, Dept Nephrol, Dept Dialysis & Transplantat, Vicenza, Italy

[27] Univ Pittsburgh, Ctr Crit Care Nephrol, Dept Crit Care Med, Pittsburgh, PA USA

来源：

NATURE REVIEWS NEPHROLOGY | 2017年 / 13卷 / 04期

关键词：

CRITICALLY-ILL PATIENTS; GLOMERULAR-FILTRATION-RATE; GELATINASE-ASSOCIATED LIPOCALIN; ANGIOTENSIN RECEPTOR BLOCKERS; REPLACEMENT THERAPY MODALITY; LONG-TERM SURVIVAL; SERUM CREATININE; RESISTIVE INDEX; STRESS TEST; HIGH-RISK;

D O I：

10.1038/nrneph.2017.2

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Consensus definitions have been reached for both acute kidney injury (AKI) and chronic kidney disease (CKD) and these definitions are now routinely used in research and clinical practice. The KDIGO guideline defines AKI as an abrupt decrease in kidney function occurring over 7 days or less, whereas CKD is defined by the persistence of kidney disease for a period of > 90 days. AKI and CKD are increasingly recognized as related entities and in some instances probably represent a continuum of the disease process. For patients in whom pathophysiologic processes are ongoing, the term acute kidney disease (AKD) has been proposed to define the course of disease after AKI; however, definitions of AKD and strategies for the management of patients with AKD are not currently available. In this consensus statement, the Acute Disease Quality Initiative (ADQI) proposes definitions, staging criteria for AKD, and strategies for the management of affected patients. We also make recommendations for areas of future research, which aim to improve understanding of the underlying processes and improve outcomes for patients with AKD.

引用

页码：241 / 257

页数：17

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