Development of a Double-Gauss Lens Based Setup for Optoacoustic Applications

被引:28
作者
Choi, Hojong [1 ]
Ryu, Jae-Myung [2 ]
Yeom, Jung-Yeol [3 ]
机构
[1] Kumoh Natl Inst Technol, Dept Med IT Convergence Engn, Gumi 39253, South Korea
[2] Kumoh Natl Inst Technol, Dept Opt Syst Engn, Gumi 39253, South Korea
[3] Korea Univ, Sch Biomed Engn, Seoul 02841, South Korea
关键词
optoacoustic applications; double-Gauss lens; transducer; PHOTOACOUSTIC MICROSCOPY; IN-VIVO; ULTRASOUND; FREQUENCY; DESIGN; TRANSDUCERS;
D O I
10.3390/s17030496
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In optoacoustic (photoacoustic) systems, different echo signal intensities such as amplitudes, center frequencies, and bandwidths need to be compensated by utilizing variable gain or time-gain compensation amplifiers. However, such electronic components can increase system complexities and signal noise levels. In this paper, we introduce a double-Gauss lens to generate a large field of view with uniform light intensity due to the low chromatic aberrations of the lens, thus obtaining uniform echo signal intensities across the field of view of the optoacoustic system. In order to validate the uniformity of the echo signal intensities in the system, an in-house transducer was placed at various positions above a tissue sample and echo signals were measured and compared with each other. The custom designed double-Gauss lens demonstrated negligible light intensity variation (+/- 1.5%) across the illumination field of view (similar to 2 cm diameter). When the transducer was used to measure echo signal from an eye of a bigeye tuna within a range of +/- 1 cm, the peak-to-peak amplitude, center frequency, and their -6 dB bandwidth variations were less than 2 mV, 1 MHz, and 6%, respectively. The custom designed double-Gauss lens can provide uniform light beam across a wide area while generating insignificant echo signal variations, and thus can lower the burden of the receiving electronics or signal processing in the optoacoustic system.
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页数:15
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