Antimicrobial susceptibility and synergy studies of Burkholderia cepacia complex isolated from patients with cystic fibrosis

被引：82

作者：

Zhou, Juyan ^{[1
]}

Chen, Yunhua ^{[1
]}

Tabibi, Setareh ^{[1
]}

Alba, Luis ^{[1
]}

Garber, Elizabeth ^{[1
]}

Saiman, Lisa ^{[1
]}

机构：

[1] Columbia Univ, Coll Phys & Surg, Dept Pediat, Div Infect Dis, New York, NY 10032 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 03期

关键词：

D O I：

10.1128/AAC.00954-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Susceptibility (18 antimicrobial agents including high-dose tobramycin) and checkerboard synergy (23 combinations) studies were performed for 2,621 strains of Burkholderia cepacia complex isolated from 1,257 cystic fibrosis patients. Minocycline, meropenem, and ceftazidime were the most active, inhibiting 38%, 26%, and 23% of strains, respectively. Synergy was rarely noted (range, 1% to 15% of strains per antibiotic combination).

引用

页码：1085 / 1088

页数：4

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