Anti-VEGF therapy as adjuvant therapy: clouds on the horizon?

被引：11
|
作者：
Schneider, Bryan P. [1 ]
Sledge, George W., Jr. [1 ]
机构：
[1] Indiana Univ, Simon Canc Ctr, Indianapolis, IN 46220 USA
来源：
BREAST CANCER RESEARCH | 2009年 / 11卷 / 03期
关键词：
PACLITAXEL PLUS BEVACIZUMAB; SUNITINIB MALATE; BREAST-CANCER;
D O I：
10.1186/bcr2250
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Anti-angiogenic therapies have demonstrated their value in the setting of advanced cancer, and are being explored for use in micrometastatic disease. Recent preclinical studies suggest that adjuvant anti-vascular endothelial growth factor (VEGF) therapies may increase the risk of metastasis. How concerning are these preclinical studies, and should they affect our willingness to explore anti-VEGF therapy in the adjuvant setting?
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页数：2
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