Synergistic activities of clarithromycin and pyrazinamide against Mycobacterium tuberculosis in human macrophages

被引：16

作者：

Mor, N ^{[1
]}

Esfandiari, A ^{[1
]}

机构：

[1] CHARLES R DREW UNIV MED & SCI,LOS ANGELES,CA 90059

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1997年 / 41卷 / 09期

关键词：

D O I：

10.1128/AAC.41.9.2035

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The combination of clarithromycin and pyrazinamide was found to be synergistic against Mycobacterium tuberculosis in human macrophages. MICs were four-to eightfold lower for this combination than they were for either drug alone. Clarithromycin and rifampin, however, had only an additive effect.

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页码：2035 / 2036

页数：2

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