Rethinking potentially inappropriate medication use in nursing homes within the Chinese population

被引:0
作者
Lin, Yu-Ning [1 ]
Tsai, Hsiu-Hsin [2 ,3 ]
Huang, Hsiu-Li [4 ]
Chang, Yue-Cune [5 ]
Shieh, Wann-Yun [6 ]
机构
[1] Cheng Hsin Gen Hosp, Dept Nursing, Taipei, Taiwan
[2] Chang Gung Univ, Coll Med, Sch Nursing, 259,Wen Hwa 1st Rd, Taoyuan 33302, Taiwan
[3] Chang Gung Mem Hosp Linkou, Dept Psychiat, Taoyuan, Taiwan
[4] Natl Taipei Univ Nursing & Hlth Sci, Coll Hlth Technol, Taipei, Taiwan
[5] Tamkang Univ, Dept Math, New Taipei, Taiwan
[6] Chang Gung Univ, Dept Comp Sci & Informat Engn, Taoyuan, Taiwan
关键词
Potentially inappropriate medication; Chinese medicine; Literature review; Hospital admission; Fall; DRUG-USE; OLDER; RESIDENTS; MEDICINE; POLYPHARMACY; SAFETY; TAIWAN; HEALTH; IMPACT; RISK;
D O I
10.1016/j.gerinurse.2020.05.001
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
This study aimed to understand the prevalence of Chinese medicine and other potentially inappropriate medications and to examine if there are relationships with emergency room visits, hospital admissions, and falls in a Chinese nursing home population. This cross-sectional descriptive study was a secondary analysis of data from 531 nursing home residents in Taiwan. Cox proportional hazard regression models were used in the analysis. Use of Chinese medicine in combination with Western medicine was observed in approximately 1% of residents. For every additional Chinese medicine used, the hazard ratio was 3.09 (p=.26) for emergency room visits and 3.22 (p=.21) for hospital admissions. For every additional nonsteroidal antiinflammatory agent used, the hazard ratio for falls was 5.42 (p=.006). Further studies with larger sample sizes are required to understand the appropriate time intervals required between administration of Chinese and Western medicine as well as to understand the drug-drug interactions. (C) 2020 Elsevier Inc. All rights reserved.
引用
收藏
页码:724 / 729
页数:6
相关论文
共 32 条
[1]   Comprehensive Literature Review of Factors Influencing Medication Safety in Nursing Homes: Using a Systems Model [J].
Al-Jumaili, Ali Azeez ;
Doucette, William R. .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2017, 18 (06) :470-488
[2]   An overview on adverse drug reactions to traditional Chinese medicines [J].
Chan, Kelvin ;
Zhang, Hongwei ;
Lin, Zhi-Xiu .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2015, 80 (04) :834-843
[3]  
Chou HJ, 2010, FORMOSA J CLIN PHARM, V18, P33
[4]   Inappropriate Drug Prescription at Nursing Home Admission [J].
Garcia-Gollarte, Fermin ;
Baleriola-Julvez, Jose ;
Ferrero-Lopez, Isabel ;
Cruz-Jentoft, Alfonso J. .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2012, 13 (01) :83.e9-83.e15
[5]   Institutionalization as a Risk Factor for Inappropriate Drug Use in the Elderly: A Swedish Nationwide Register-Based Study [J].
Haasum, Ylva ;
Fastbom, Johan ;
Johnell, Kristina .
ANNALS OF PHARMACOTHERAPY, 2012, 46 (03) :339-346
[6]   Polypharmacy and potentially inappropriate medications: a cross-sectional analysis among 451 nursing homes in France [J].
Herr, Marie ;
Grondin, Helene ;
Sanchez, Stephane ;
Armaingaud, Didier ;
Blochet, Caroline ;
Vial, Antoine ;
Denormandie, Philippe ;
Ankri, Joel .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2017, 73 (05) :601-608
[7]   Influence of age and sex on hospitalization of nursing home residents: A cross-sectional study from Germany [J].
Hoffmann, Falk ;
Schmiemann, Guido .
BMC HEALTH SERVICES RESEARCH, 2017, 17
[8]   Systematic overview of warfarin and its drug and food interactions [J].
Holbrook, AM ;
Pereira, JA ;
Labiris, R ;
McDonald, H ;
Douketis, JD ;
Crowther, M ;
Wells, PS .
ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (10) :1095-1106
[9]   Prescribing for older people discharged from the acute sector to residential aged-care facilities [J].
Hopcroft, P. ;
Peel, N. M. ;
Poudel, A. ;
Scott, I. A. ;
Gray, L. C. ;
Hubbard, R. E. .
INTERNAL MEDICINE JOURNAL, 2014, 44 (10) :1034-1037
[10]  
Huang LH, 2010, J LONG TERM CARE, V14, P277