Arylchlorogermanes/TBAF/"Moist" Toluene: A Promising Combination for Pd-Catalyzed Germyl-Stille Cross-Coupling

被引：25

作者：

Zhang, Zun-Ting ^{[1
]}

Pitteloud, Jean-Philippe ^{[1
]}

Cabrera, Laura ^{[1
]}

Liang, Yong ^{[1
]}

Toribio, Myrdich ^{[1
]}

Wnuk, Stanislaw F. ^{[1
]}

机构：

[1] Florida Int Univ, Dept Chem & Biochem, Miami, FL 33199 USA

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 04期

关键词：

BIARYL SYNTHESIS; ARYL HALIDES; TETRABUTYLAMMONIUM TRIPHENYLDIFLUOROSILICATE; ALKYNYL GERMATRANES; KINETIC-ANALYSIS; ORGANIC HALIDES; PALLADIUM; TRIS(TRIMETHYLSILYL)GERMANES; REAGENTS; VINYL;

D O I：

10.1021/ol9028918

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The trichlorophenyl,- dichlorodiphenyl,- and chlorotriphenylgermanes undergo Pd-catalyzed cross-couplings with aryl bromides and iodides in the presence of TBAF in toluene with addition of the measured amount of water. One chloride ligand on the Ge center allows efficient activation by fluoride to promote transfer of one, two, or three phenyl groups from the organogermane precursors.

引用

页码：816 / 819

页数：4

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