Vital dyes in macular hole surgery

被引:3
作者
Popescu, Ioana Stella [1 ]
Musat, Ovidiu [2 ]
Stanca, Simona [3 ]
Cernat, Corina Cristina [1 ]
Patoni, Cristina [4 ]
Negru, Serban [5 ]
Teodoru, Adrian [6 ]
Feier, Horia [7 ]
Danielescu, Ciprian [8 ]
机构
[1] Victor Babes Univ Med & Pharm Timisoara, Dept Ophthalmol, Timisoara 300041, Romania
[2] Dr Carol Davila Cent Mil Emergency Univ Hosp, Dept Ophthalmol, Bucharest 010825, Romania
[3] Carol Davila Univ Med & Pharm, Dept Pediat, Bucharest 050474, Romania
[4] Dr Carol Davila Cent Mil Emergency Univ Hosp, Dept Gastroenterol, Bucharest 010825, Romania
[5] Victor Babes Univ Med & Pharm Timisoara, Dept Oncol, Timisoara 300239, Romania
[6] Lucian Blaga Univ Sibiu, Dept Ophthalmol, 2A Lucian Blaga St, Sibiu 550169, Romania
[7] Victor Babes Univ Med & Pharm Timisoara, Dept Cardiovasc Surg, 13A Gheorghe Adam St, Timisoara 300041, Romania
[8] Grigore T Popa Univ Med & Pharm, Dept Ophthalmol, Iasi 700115, Romania
关键词
macular hole; internal limiting membrane; cromovitrectomy; Brilliant Blue G; lutein and zeaxanthin dyes; pars plana vitrectomy; intraocular dyes; staining technique; BRILLIANT BLUE; OUTCOMES; LUTEIN; LASER;
D O I
10.3892/etm.2021.9959
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Currently, surgical techniques, such as internal limiting membrane peeling, are used widely for macular holes, macular puckers, epiretinal membranes, diabetic macular edema, retinal detachment, retinal vein occlusions, vitreomacular traction, optic pit maculopathy, and Terson syndrome. This study aimed to highlight any differences regarding visual acuity and ocular tomography coherence changes after staining the internal limiting membrane with dilutions of Brilliant Blue G vs. lutein/zeaxanthin-based dyes. This study involved 30 eyes of 30 patients who had undergone posterior pole vitrectomy for idiopathic stage 4 macular hole. The study lot was divided in two subgroups, 15 eyes colored with Brilliant Blue and the other 15 eyes colored with lutein and zeaxanthin dyes. The association between visual prognosis, ocular tomography coherence changes and intraocular pressure was analyzed. The surgical treatment with required endoillumination levels and a 2-min period of dye using the Alcon Constellation Vision System had no negative impact on cell viability and improved visual acuity by 30%. Staining makes it easier to remove, to be quick and precise while performing macular surgeries. In has been observed that lutein and zeaxanthin dyes offer an intraoperative protective screen that protects photoreceptors more than Brilliant Blue while performing pars plana vitrectomy. Both study groups had good results in time. Surgical visualization is an evolving technology.
引用
收藏
页数:6
相关论文
共 31 条
[1]  
ABRAMS GW, 1978, ARCH OPHTHALMOL-CHIC, V96, P521
[2]   TECHNIQUES, RATIONALE, AND OUTCOMES OF INTERNAL LIMITING MEMBRANE PEELING [J].
Almony, Arghavan ;
Nudleman, Eric ;
Shah, Gaurav K. ;
Blinder, Kevin J. ;
Eliott, Dean B. ;
Mittra, Robert A. ;
Tewari, Asheesh .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2012, 32 (05) :877-891
[3]   Soluble lutein in combination with brilliant blue as a new dye for chromovitrectomy [J].
Badaro, Emmerson ;
Furlani, Bruno ;
Prazeres, Juliana ;
Maia, Mauricio ;
Souza Lima, Acacio Alves ;
Souza-Martins, Diogo ;
Muccioli, Cristina ;
Adami Lucatto, Luiz Filipe ;
Belfort, Rubens, Jr. .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2014, 252 (07) :1071-1078
[4]  
Balica NC, 2019, ROM J MORPHOL EMBRYO, V60, P267
[5]   Pathogenesis and Management of Macular Hole: Review of Current Advances [J].
Bikbova, Guzel ;
Oshitari, Toshiyuki ;
Baba, Takayuki ;
Yamamoto, Shuichi ;
Mori, Keisuke .
JOURNAL OF OPHTHALMOLOGY, 2019, 2019
[6]  
Boruga O, 2017, ROM J MORPHOL EMBRYO, V58, P1461
[7]  
Brao-Lencart J., 2012, NEW LUTEIN BASED DYE
[8]   Dye Solutions Based on Lutein and Zeaxanthin: In Vitro and In Vivo Analysis of Ocular Toxicity Profiles [J].
Casaroli-Marano, Ricardo P. ;
Sousa-Martins, Diogo ;
Martinez-Conesa, Eva M. ;
Badaro, Emmerson ;
Nunes, Renata Portella ;
Lima-Filho, Acacio A. S. ;
Rodrigues, Eduardo B. ;
Belfort, Rubens, Jr. ;
Maia, Mauricio .
CURRENT EYE RESEARCH, 2015, 40 (07) :707-718
[9]  
Christensen Ulrik Correll, 2009, Acta Ophthalmol, V87 Thesis 2, P1, DOI 10.1111/j.1755-3768.2009.01777.x
[10]  
Dubey Arvind Kumar, 2003, Indian J Ophthalmol, V51, P286