Epinephrine Use during Newborn Resuscitation

被引：26

作者：

Kapadia, Vishal S. ^{[1
]}

Wyckoff, Myra H. ^{[1
]}

机构：

[1] Univ Texas Southwestern Med Ctr Dallas, Pediat, Dallas, TX 75390 USA

来源：

FRONTIERS IN PEDIATRICS | 2017年 / 5卷

关键词：

epinephrine; neonatal resuscitation; asphyxia; newborn; delivery room; infants; HIGH-DOSE EPINEPHRINE; ROOM CARDIOPULMONARY-RESUSCITATION; EMERGENCY CARDIOVASCULAR CARE; ASPHYXIAL CARDIAC-ARREST; DELIVERY ROOM; NEONATAL RESUSCITATION; TREATMENT RECOMMENDATIONS; ENDOTRACHEAL EPINEPHRINE; INTERNATIONAL CONSENSUS; MYOCARDIAL-PERFUSION;

D O I：

10.3389/fped.2017.00097

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Epinephrine use in the delivery room for resuscitation of the newborn is associated with significant morbidity and mortality. Evidence for optimal dose, timing, and route of administration of epinephrine during neonatal resuscitation comes largely from extrapolated adult or animal literature. In this review, we provide the current recommendations for use of epinephrine during neonatal resuscitation and also the evidence behind these recommendations. In addition, we review the current proposed mechanism of action of epinephrine during neonatal resuscitation, review its adverse effects, and identify gaps in knowledge requiring urgent research.

引用

页数：8

共 76 条

[1] Intraosseous is faster and easier than umbilical venous catheterization in newborn emergency vascular access models [J].

Abe, KK ;

Blum, GT ;

Yamamoto, LG .

AMERICAN JOURNAL OF EMERGENCY MEDICINE, 2000, 18 (02) :126-129

[2] Enhanced brain stem 5HT2A receptor function under neonatal hypoxic insult: role of glucose, oxygen, and epinephrine resuscitation [J].

Anju, T. R. ;

Korah, P. K. ;

Jayanarayanan, S. ;

Paulose, C. S. .

MOLECULAR AND CELLULAR BIOCHEMISTRY, 2011, 354 (1-2) :151-160

[3] Alterations in cortical GABAB receptors in neonatal rats exposed to hypoxic stress: role of glucose, oxygen, and epinephrine resuscitation [J].

Anju, T. R. ;

Abraham, Pretty Mary ;

Antony, Sherin ;

Paulose, C. S. .

MOLECULAR AND CELLULAR BIOCHEMISTRY, 2010, 343 (1-2) :1-11

[4] Where name and image meet - the argument for "adrenaline" [J].

Aronson, JK .

BMJ-BRITISH MEDICAL JOURNAL, 2000, 320 (7233) :506-509

[5] Use and efficacy of endotracheal versus intravenous epinephrine during neonatal cardiopulmonary resuscitation in the delivery room [J].

Barber, Chad A. ;

Wyckoff, Myra H. .

PEDIATRICS, 2006, 118 (03) :1028-1034

[6] A randomized, blinded trial of high-dose epinephrine versus standard-dose epinephrine in a swine model of pediatric asphyxial cardiac arrest [J].

Berg, RA ;

Otta, CW ;

Kern, KB ;

Hilwig, RW ;

Sanders, AB ;

Henry, CP ;

Ewy, GA .

CRITICAL CARE MEDICINE, 1996, 24 (10) :1695-1700

[7] THE EFFECT OF HIGH-DOSE PHENYLEPHRINE VERSUS EPINEPHRINE ON REGIONAL CEREBRAL BLOOD-FLOW DURING CPR [J].

BROWN, CG ;

WERMAN, HA ;

DAVIS, EA ;

KATZ, S ;

HAMLIN, RL .

ANNALS OF EMERGENCY MEDICINE, 1987, 16 (07) :743-748

[8] EFFECTS OF GRADED DOSES OF EPINEPHRINE DURING ASPHYXIA-INDUCED BRADYCARDIA IN NEWBORN LAMBS [J].

BURCHFIELD, DJ ;

PREZIOSI, MP ;

LUCAS, VW ;

FAN, J .

RESUSCITATION, 1993, 25 (03) :235-244

[9] Potential negative effects of epinephrine on carotid blood flow and ETCO2 during active compression-decompression CPR utilizing an impedance threshold device [J].

Burnett, Aaron M. ;

Segal, Nicolas ;

Salzman, Joshua G. ;

McKnite, M. Scott ;

Frascone, Ralph J. .

RESUSCITATION, 2012, 83 (08) :1021-1024

[10] Acetylcholine esterase activity and behavioral response in hypoxia induced neonatal rats: Effect of glucose, oxygen and epinephrine supplementation [J].

Chathu, Finla ;

Krishnakumar, Amee ;

Paulose, Cheramadathikudyil S. .

BRAIN AND COGNITION, 2008, 68 (01) :59-66

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