Secondary organizing pneumonia after coronavirus disease 2019: Two cases

被引：14

作者：

Kanaoka, Kensuke ^{[1
]}

Minami, Seigo ^{[1
,2
]}

Ihara, Shoichi ^{[1
]}

Tanaka, Tsunehiro ^{[1
]}

Yasuoka, Hironao ^{[3
]}

Komuta, Kiyoshi ^{[1
]}

机构：

[1] Daini Osaka Police Hosp, Dept Resp Med, Tennoji Ku, 2-6-40 Karasugatsuji, Osaka 5438922, Japan

[2] Osaka Police Hosp, Dept Resp Med, Tennoji Ku, 10-31 Kitayama Cho, Osaka 5430035, Japan

[3] Osaka Police Hosp, Dept Pathol, Tennoji Ku, 10-31 Kitayama Cho, Osaka 5430035, Japan

来源：

RESPIRATORY MEDICINE CASE REPORTS | 2021年 / 32卷

关键词：

COVID-19; SARS-CoV-2; Organizing pneumonia; Transbronchial lung biopsy; Corticosteroids; Diffusion capacity;

D O I：

10.1016/j.rmcr.2021.101356

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Coronavirus disease 2019 (COVID-19) has been reported to induce persistent symptoms even after an acute phase. However, the pathophysiology and treatment of this condition have been unclear. We report two patients who recovered from COVID-19, but presented persistent respiratory symptoms. Their respiratory conditions deteriorated, and computed tomography showed remaining ground glass opacities and consolidations. The pathological findings of transbronchial lung biopsy corresponded to organizing pneumonia. We diagnosed them with secondary organizing pneumonia after COVID-19. Subsequently, we administered systemic corticosteroids. Their symptoms, oxygenations, radiologic findings, and pulmonary functions rapidly improved after the treatment of corticosteroids. The two cases showed that secondary organizing pneumonia may be a cause of persistent respiratory failure after COVID-19. In this condition, corticosteroids may be effective.

引用

页数：4

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