A New Formulation Based on Ozonated Sunflower Seed Oil: In Vitro Antibacterial and Safety Evaluation

被引：20

作者：

Serio, Francesca ^{[1
]}

Pizzolante, Graziano ^{[1
]}

Cozzolino, Giuseppe ^{[2
]}

D'Alba, Maria ^{[3
]}

Bagordo, Francesco ^{[1
]}

De Giorgi, Mattia ^{[1
]}

Grassi, Tiziana ^{[1
]}

Idolo, Adele ^{[1
]}

Guido, Marcello ^{[1
]}

De Donno, Antonella ^{[1
]}

机构：

[1] Univ Salento, Dept Biol & Environm Sci & Technol, I-73100 Lecce, Italy

[2] Hosp Cardinal G Panico, Dept Vasc & Endovasc Surg, I-73039 Tricase, Italy

[3] Hosp V Delli Ponti, Dept Nephrol & Dialysis, I-73020 Scorrano, Italy

来源：

OZONE-SCIENCE & ENGINEERING | 2017年 / 39卷 / 03期

关键词：

Ozone; Antibacterial Activity; Cytotoxicity; Dermatological Gel; Ozonated Sunflower Seed Oil; Preservative Efficiency; SOFT-TISSUE INFECTIONS; ALPHA-LIPOIC ACID; GOLD NANOPARTICLES; SKH1; MICE; SKIN; EPIDEMIOLOGY; ANTIOXIDANT; RESISTANCE; OLEOZON; SYSTEMS;

D O I：

10.1080/01919512.2016.1272405

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The objective of this study was to investigate the potential in vitro biological properties of Oz.Or.Oil 30, a new formulation composed of 30% ozonated sunflower seed oil, which is believed to keep skin smooth and moisturized, supporting repair processes, tissue regeneration and re-epithelialization of wounds. The antibacterial activity, the qualitative and quantitative evaluation of the cytotoxic effect of the formulation on cultures of Vero cells and 3T3 fibroblasts showed that Oz.Or.Oil 30 merits further in vivo study using clinical-laboratory correlations, because it could be suggested as an alternative therapy against bacterial and fungal diseases.

引用

页码：139 / 147

页数：9

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