Design and interpretation of clinical research studies in oral medicine: a brief review

被引:1
作者
Atkinson, J. C. [1 ]
Clark, D. B. [2 ]
机构
[1] Natl Inst Dent & Craniofacial Res, Clin Res Ctr, NIH, 6701 Democracy Blvd,Room 634,MSC 4878, Bethesda, MD 20892 USA
[2] Natl Inst Dent & Craniofacial Res, Behav & Social Sci Res Branch, NIH, Bethesda, MD 20892 USA
关键词
clinical research; epidemiology; oral medicine; RISK; SELECTION; CANCER; METAANALYSES; QUALITY; TRIALS;
D O I
10.1111/odi.12385
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The objective of this short review is to help researchers improve the designs of their clinical studies. Also included is a discussion of the level of evidence provided by the various clinical research study designs.
引用
收藏
页码:87 / 92
页数:6
相关论文
共 50 条
[41]   Key Issues in Clinical and Epidemiological Research in Complementary and Alternative Medicine - a Systematic Literature Review [J].
Fischer, H. Felix ;
Junne, Florian ;
Witt, Claudia ;
von Ammon, Klaus ;
Cardini, Francesco ;
Fonnebo, Vinjar ;
Johannessen, Helle ;
Lewith, George ;
Uehleke, Bernhard ;
Weidenhammer, Wolfgang ;
Brinkhaus, Benno .
FORSCHENDE KOMPLEMENTARMEDIZIN, 2012, 19 :51-60
[42]   World Workshop on Oral Medicine VII: Clinical evidence of differential expression of lncRNAs in oral squamous cell carcinoma: A scoping review [J].
Pentenero, Monica ;
Bowers, Leah M. ;
Jayasinghe, Ruwan ;
Yap, Tami ;
Cheong, Sok Ching ;
Kerr, Alexander Ross ;
Farah, Camile S. ;
Alevizos, Ilias .
ORAL DISEASES, 2019, 25 :88-101
[43]   Youtube™ Content Analysis as a Means of Information in Oral Medicine: A Systematic Review of the Literature [J].
Romano, Antonio ;
Fiori, Fausto ;
Petruzzi, Massimo ;
Della Vella, Fedora ;
Serpico, Rosario .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2022, 19 (09)
[44]   Circular RNAs: Diversity of Functions and a Regulatory Nova in Oral Medicine: A Pilot Review [J].
Wang, Hong ;
Feng, Cheng ;
Wang, Meng ;
Yang, Shuangyan ;
Wei, Fulan .
CELL TRANSPLANTATION, 2019, 28 (07) :819-830
[45]   Sequencing studies in human genetics: design and interpretation [J].
Goldstein, David B. ;
Allen, Andrew ;
Keebler, Jonathan ;
Margulies, Elliott H. ;
Petrou, Steven ;
Petrovski, Slave ;
Sunyaev, Shamil .
NATURE REVIEWS GENETICS, 2013, 14 (07) :460-470
[46]   DO ORAL CARE AND REHABILITATION IMPROVE COGNITIVE FUNCTION? A SYSTEMATIC REVIEW OF CLINICAL STUDIES [J].
Inamochi, Yuka ;
Ogino, Yoichiro ;
Harada, Kae ;
Fueki, Kenji ;
Ayukawa, Yasunori ;
Nishimura, Masahiro ;
Maekawa, Kenji ;
Kang, Youngnam ;
Hirai, Toshihiro ;
Kuboki, Takuo .
JOURNAL OF EVIDENCE-BASED DENTAL PRACTICE, 2024, 24 (01)
[47]   Research Question, Objectives, and Endpoints in Clinical and Oncological Research: A Comprehensive Review [J].
Singh, Addanki Purna ;
Shahapur, Praveen R. ;
Vadakedath, Sabitha ;
Bharadwaj, Vallab Ganesh ;
Kumar, Dr Pranay ;
Pinnelli, Venkata BharatKumar ;
Godishala, Vikram ;
Kandi, Venkataramana .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (09)
[48]   Tasks of research in forensic medicine - different study types in clinical research and forensic medicine [J].
Madea, Burkhard ;
Saukko, Pekka ;
Musshoff, Frank .
FORENSIC SCIENCE INTERNATIONAL, 2007, 165 (2-3) :92-97
[49]   Statistics in Brief: Study Designs in Orthopaedic Clinical Research [J].
Jolles, Brigitte M. ;
Martin, Estelle .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2011, 469 (03) :909-913
[50]   Representing Clinical Knowledge in Oral Medicine Using Ontologies [J].
Gustafsson, Marie ;
Falkman, Goran .
CONNECTING MEDICAL INFORMATICS AND BIO-INFORMATICS, 2005, 116 :743-748