The Effect of Branching on the One- and Two-Photon Absorption, Cell Viability, and Localization of Cationic Triarylborane Chromophores with Dipolar versus Octupolar Charge Distributions for Cellular Imaging

被引：50

作者：

Griesbeck, Stefanie ^{[1
,2
]}

Michail, Evripidis ^{[3
]}

Rauch, Florian ^{[1
,2
]}

Ogasawara, Hiroaki ^{[4
]}

Wang, Chenguang ^{[4
]}

Sato, Yoshikatsu ^{[4
]}

Edkins, Robert M. ^{[1
,2
,5
]}

Zhang, Zuolun ^{[1
,2
,6
]}

Taki, Masayasu ^{[4
]}

Lambert, Christoph ^{[3
]}

Yamaguchi, Shigehiro ^{[4
]}

Marder, Todd B. ^{[1
,2
]}

机构：

[1] Julius Maximilians Univ Wurzburg, Inst Anorgan Chem, D-97074 Wurzburg, Germany

[2] Julius Maximilians Univ Wurzburg, Inst Sustainable Chem & Catalysis Boron, D-97074 Wurzburg, Germany

[3] Julius Maximilians Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany

[4] Nagoya Univ, Inst Transformat Biomol, Nagoya, Aichi, Japan

[5] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow, Lanark, Scotland

[6] Jilin Univ, Coll Chem, State Key Lab Supramol Struct & Mat, Qianjin St, Changchun, Jilin, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2019年 / 25卷 / 57期

关键词：

boranes; cell imaging; fluorescence; lysosome; two-photon excited fluorescence; NONLINEAR-OPTICAL-PROPERTIES; A-PI-A; MOLECULAR-STRUCTURES; FLUORESCENT-PROBE; TRIVALENT BORON; SINGLE-PHOTON; PHOTOPHYSICAL PROPERTIES; COOPERATIVE ENHANCEMENT; FLUOROPHORES SYNTHESIS; ORGANOBORON COMPOUNDS;

D O I：

10.1002/chem.201902461

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two different chromophores, namely a dipolar and an octupolar system, were prepared and their linear and nonlinear optical properties as well as their bioimaging capabilities were compared. Both contain triphenylamine as the donor and a triarylborane as the acceptor, the latter modified with cationic trimethylammonio groups to provide solubility in aqueous media. The octupolar system exhibits a much higher two-photon brightness, and also better cell viability and enhanced selectivity for lysosomes compared with the dipolar chromophore. Furthermore, both dyes were applied in two-photon excited fluorescence (TPEF) live-cell imaging.

引用

页码：13164 / 13175

页数：12

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