Requirements to produce fumarprotocetraric acid using alginate-immobilized cells of Cladonia verticillaris

被引：5
|
作者：
Fontaniella, B
Legaz, ME
Pereira, EC
Sebastián, B
Vicente, C [1 ]
机构：
[1] Univ Complutense, Fac Biol, Dept Plant Physiol, E-28040 Madrid, Spain
[2] Univ Fed Pernambuco, CCB, Dept Bot, CFCH,Dept Ciencias Geog, BR-50640901 Recife, PE, Brazil
来源：
BIOTECHNOLOGY LETTERS | 2000年 / 22卷 / 10期
关键词：
alginate; Cladonia verticillaris; fumarprotocetraric acid; immobilization;
D O I：
10.1023/A:1005673715916
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The biosynthesis of the depsidone, fumarprotocetraric acid, a compound previously considered to be only produced by lichens, has been confirmed by using alginate-immobilized cells of Cladonia verticillaris. Immobilized cells only produce the depsidone when they are supplemented with FMN and acetate. This implies that fumaric acid which esterifies an alcohol function in the C3 of a depsidone precursor is added through a reducing, flavin-dependent, coupling reaction that uses the pool of succinyl-CoA from the fungal partner.
引用
收藏
页码：813 / 817
页数：5
相关论文
共 50 条
  • [1] Requirements to produce fumarprotocetraric acid using alginate-immobilized cells of Cladonia verticillaris
    Blanca Fontaniella
    María-Estrella Legaz
    Eugênia C. Pereira
    Betania Sebastián
    C. Vicente
    Biotechnology Letters, 2000, 22 : 813 - 817
  • [2] PRODUCTION OF RIBITOL BY ALGINATE-IMMOBILIZED CELLS OF THE LICHEN CLADONIA-VERTICILLARIS
    PEREIRA, EC
    MOLINA, MDC
    PEDROSA, MM
    SOLAS, MT
    VICENTE, C
    LEGAZ, ME
    ANALES DE QUIMICA, 1995, 91 (3-4): : 253 - 259
  • [3] Expectorant and antioxidant activities of purified fumarprotocetraric acid from Cladonia verticillaris lichen in mice
    de Barros Alves, Glicia Maria
    de Sousa Maia, Maria Bernadete
    Franco, Eryvelton de Souza
    Galvao, Andre Martins
    da Silva, Teresinha Goncalves
    Gomes, Renata Miranda
    Martins, Monica Barroso
    da Silva Falcao, Emerson Peter
    Machado Barbosa de Castro, Celia Maria
    da Silva, Nicacio Henrique
    PULMONARY PHARMACOLOGY & THERAPEUTICS, 2014, 27 (02) : 139 - 143
  • [4] Effect of fumarprotocetraric acid isolated the Lichen Cladonia verticillaris on tracheobronchial phenol red excretion in mice
    Duarte, G. P.
    Alves, G. D.
    Franco, E. D.
    Melo, R. G.
    Cordeiro, D. P.
    Pereira, E. C.
    Silva, N. H.
    Maia, M. D.
    PLANTA MEDICA, 2011, 77 (12) : 1447 - 1447
  • [5] STABILITY OF ALGINATE-IMMOBILIZED ALGAL CELLS
    DAINTY, AL
    GOULDING, KH
    ROBINSON, PK
    SIMPKINS, I
    TREVAN, MD
    BIOTECHNOLOGY AND BIOENGINEERING, 1986, 28 (02) : 210 - 216
  • [6] INVOLVEMENT OF PHYTOCHROME-MEDIATED CYCLIC-AMP IN THE SYNTHESIS AND DEPOSITION OF FUMARPROTOCETRARIC ACID ON CORTICAL HYPHAE OF CLADONIA-VERTICILLARIS
    MATEOS, JL
    PEDROSA, MM
    MOLINA, MD
    PEREIRA, EC
    VICENTE, C
    LEGAZ, ME
    PLANT PHYSIOLOGY AND BIOCHEMISTRY, 1993, 31 (05) : 667 - 674
  • [7] Improved organic acid production by calcium alginate-immobilized propionibacteria
    Dept. of Food Sci. and Hum. Nutr., Ctr. Crops Utiliz. Res., Iowa S., Ames, IA, United States
    不详
    Enzyme Microb. Technol., 5 (409-414):
  • [8] 11-ALPHA-HYDROXYLATION OF PROGESTERONE USING MODIFIED ALGINATE-IMMOBILIZED CELLS
    CHEN, KC
    YIN, WS
    TIU, C
    HOUNG, JY
    ENZYME AND MICROBIAL TECHNOLOGY, 1994, 16 (07) : 551 - 555
  • [9] Improved organic acid production by calcium alginate-immobilized propionibacteria
    Rickert, DA
    Glatz, CE
    Glatz, BA
    ENZYME AND MICROBIAL TECHNOLOGY, 1998, 22 (05) : 409 - 414
  • [10] Purification of alginate and feasible production of monoclonal antibodies by the alginate-immobilized hybridoma cells
    Selimoglu, S. Mert
    Ayyildiz-Tamis, Duygu
    Gurhan, Ismet Deliloglu
    Elibol, Murat
    JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2012, 113 (02) : 233 - 238
12345