Menstrual Patterns and Treatment of Heavy Menstrual Bleeding in Adolescents with Bleeding Disorders

被引:25
作者
Dowlut-McElroy, Tazim [1 ]
Williams, Karen B. [2 ]
Carpenter, Shannon L. [3 ]
Strickland, Julie L. [1 ,4 ]
机构
[1] Univ Missouri, Sch Med, Dept Obstet & Gynecol, Kansas City, MO 64108 USA
[2] Univ Missouri, Sch Med, Dept Biomed & Hlth Informat, Kansas City, MO 64108 USA
[3] Childrens Mercy Hosp, Sect Hematol, Div Hematol Oncol Bone Marrow Transplant, Kansas City, MO 64108 USA
[4] Childrens Mercy Hosp, Dept Surg, Sect Gynecol Surg, Kansas City, MO 64108 USA
关键词
Bleeding disorder; Adolescent; Menstrual patterns; Heavy menstrual bleeding; MENORRHAGIA; PREVALENCE; FEMALES; WOMEN;
D O I
10.1016/j.jpag.2015.03.001
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Study Objective: To characterize menstrual bleeding patterns and treatment of heavy menstrual bleeding in adolescents with bleeding disorders Design, Setting, and Participants: We conducted a retrospective review of female patients aged nine to 21 years with known bleeding disorders who attended a pediatric gynecology, hematology, and comprehensive hematology/gynecology clinic at a children's hospital in a metropolitan area. Main Outcome Measures: Prevalence of heavy menstrual bleeding at menarche, prolonged menses, and irregular menses among girls with bleeding disorders and patterns of initial and subsequent treatment for heavy menstrual bleeding in girls with bleeding disorders. Results: Of 115 participants aged nine to 21 years with known bleeding disorders, 102 were included in the final analysis. Of the 69 postmenarcheal girls, almost half (32/69, 46.4%) noted heavy menstrual bleeding at menarche. Girls with von Willebrand disease were more likely to have menses lasting longer than seven days. Only 28% of girls had discussed a treatment plan for heavy menstrual bleeding before menarche. Hormonal therapy was most commonly used as initial treatment of heavy menstrual bleeding. Half (53%) of the girls failed initial treatment. Combination (hormonal and non-hormonal therapy) was more frequently used for subsequent treatment. Conclusions: Adolescents with bleeding disorders are at risk of heavy bleeding at and after menarche. Consultation with a pediatric gynecologist and/or hematologist prior to menarche may be helpful to outline abnormal patterns of menstrual bleeding and to discuss options of treatment in the event of heavy menstrual bleeding.
引用
收藏
页码:499 / 501
页数:3
相关论文
共 50 条
[1]   Heavy Menstrual Bleeding in Adolescents [J].
Haamid, Fareeda ;
Sass, Amy E. ;
Dietrich, Jennifer E. .
JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY, 2017, 30 (03) :335-340
[2]   Diagnosis of Bleeding Disorders in Adolescents Hospitalized for Heavy Menstrual Bleeding [J].
Amos, Lauren E. ;
Sherman, Ashley K. ;
Carpenter, Shannon L. .
TH OPEN, 2022, 06 (03) :e291-e298
[3]   Screening and Management of Bleeding Disorders in Adolescents With Heavy Menstrual Bleeding [J].
Adeyemi-Fowode, Oluyemisi ;
Simms-Cendan, Judith .
OBSTETRICS AND GYNECOLOGY, 2019, 134 (03) :E71-E83
[4]   Management of heavy menstrual bleeding in adolescents [J].
Sokkary, Nancy ;
Dietrich, Jennifer E. .
CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2012, 24 (05) :275-280
[5]   Diagnosis and Management of Heavy Menstrual Bleeding and Bleeding Disorders in Adolescents [J].
Borzutzky, Claudia ;
Jaffray, Julie .
JAMA PEDIATRICS, 2020, 174 (02) :186-194
[6]   Assessment of rare bleeding disorders in adolescents with heavy menstrual bleeding [J].
Sharma, Ruchika ;
Johnson, Victoria ;
Pan, Amy ;
Sellers, Austin ;
Betensky, Marisol ;
Goldenberg, Neil ;
Flood, Veronica H. .
HAEMOPHILIA, 2024, 30 (02) :490-496
[7]   Platelet function defects in adolescents with heavy menstrual bleeding [J].
Mills, H. L. ;
Abdel-Baki, M. S. ;
Teruya, J. ;
Dietrich, J. E. ;
Shah, M. D. ;
Mahoney, D., Jr. ;
Yee, D. L. ;
Srivaths, L. V. .
HAEMOPHILIA, 2014, 20 (02) :249-254
[8]   Bleeding disorders in adolescents with heavy menstrual bleeding in a multicenter prospective US cohort [J].
Zia, Ayesha ;
Jain, Shilpa ;
Kouides, Peter ;
Zhang, Song ;
Gao, Ang ;
Salas, Niavana ;
Lau, May ;
Wilson, Ellen ;
DeSimone, Nicole ;
Sarode, Ravi .
HAEMATOLOGICA, 2020, 105 (07) :1969-1976
[9]   The Evaluation of Bleeding Diathesis in Adolescents with Heavy Menstrual Bleeding [J].
Evim, Melike Sezgin ;
Baytan, Birol ;
Gunes, Adalet Meral .
GUNCEL PEDIATRI-JOURNAL OF CURRENT PEDIATRICS, 2018, 16 (02) :160-169
[10]   Levonorgestrel-Releasing Intrauterine Device Use in Female Adolescents with Heavy Menstrual Bleeding and Bleeding Disorders: Single Institution Review [J].
Adeyemi-Fowode, Oluyemisi A. ;
Santos, Xiomara M. ;
Dietrich, Jennifer E. ;
Srivaths, Lakshmi .
JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY, 2017, 30 (04) :479-483