A novel and highly efficient method for the silylation of alcohols with hexamethyldisilazane (HMDS) catalyzed by recyclable sulfonic acid-functionalized ordered nanoporous silica

被引：113

作者：

Zareyee, Daryoush

Karimi, Babak

机构：

[1] Inst Adv Studies Basic Sci, Dept Chem, Zanjan, Iran

[2] Inst Fundamental Res, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 07期

关键词：

solid acids; protecting groups; green chemistry; solid sulphonic acid; hexamethyldisilazane; catalysts;

D O I：

10.1016/j.tetlet.2006.12.030

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Silylation of alcohols with hexamethyldisilazane (HMDS) in dichloromethane provides the corresponding silyl ethers in almost quantitative yields at room temperature using 1-3 mol% of sulfonic acid - function alized silica. Additionally, the catalyst displays a high activity and thermal stability (up to 240 degrees C) and it can be easily recovered and reused for at least 20 reaction cycles without loss of reactivity. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1277 / 1280

页数：4

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[1] CONSIDERED AS REAGENTS AND SYNTHETIC METHODS .46. 1,8-DIAZABICYCLO[5.4.0]UNDEC-7-ENE(DBU) - AN EFFECTIVE BASE FOR THE INTRODUCTION OF TERT-BUTYLDIMETHYLSILYL GROUP IN ORGANIC-COMPOUNDS [J].