A General Proline-Catalyzed Synthesis of 4,5-Disubstituted N-Sulfonyl-1,2,3-Triazoles from 1,3-Dicarbonyl Compounds and Sulfonyl Azide

被引：14

作者：

Rajasekar, Shanmugam ^{[1
]}

Anbarasan, Pazhamalai ^{[1
]}

机构：

[1] Indian Inst Technol Madras, Dept Chem, Chennai 600036, Tamil Nadu, India

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2019年 / 14卷 / 24期

关键词：

1; 3-dicarbonyl compounds; annulation; organocatalysis; proline; triazoles; AZIDOPHENYL ARYLSELENIDES; ORGANOCATALYTIC SYNTHESIS; CYCLOADDITION; 1,2,3-TRIAZOLES; ALKYNES; TRIAZOLES; TRANSANNULATION; BONDS;

D O I：

10.1002/asia.201901015

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient proline-catalyzed synthesis of 4,5-disubstituted-N-sulfonyl-1,2,3-triazoles has been accomplished from 1,3-dicarbonyl compounds and sulfonyl azides. The developed reaction is suitable for various symmetrical and unsymmetrical 1,3-dicarbonyl compounds, tolerates various functional groups and affords 4,5-disubstituted-N-sulfonyl-1,2,3-triazoles in good yield with excellent regioselectivity. Rhodium-catalyzed denitrogenative functionalization of 4,5-disubstituted-N-sulfonyl-1,2,3-triazoles further demonstrates their utility in organic synthesis.

引用

页码：4563 / 4567

页数：5

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